Dynamic Multimodal Monitoring for Ultrasound Guided Peripheral Nerve Blockade

Monitoring Combining Neurostimulation and Ultrasound Guidance During the Realization of a Peripheral Nerve Block: Value of Objective Measurement of the Pressure of Injection of the Local Anesthetic

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02737137

Enrollment

120

Registered

2016-04-13

Start date

2016-01-31

Completion date

2017-01-31

Last updated

2016-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthopedic Surgery

Brief summary

In clinical practice, local anesthetic injection pressure monitoring is performed manually or by a pressure transducer according to the availability of the equipment or preferences of clinicians. To date, no comparative study has measured the advantages of this measure during PNB. The aim of this study is to evaluate injection pressure monitoring in order to reduce the risk of intraneural injection during peripheral nerve blocks

Detailed description

Current recommendations for peripheral nerve block (PNB) procedure advocate combining ultrasound guidance and nerve stimulation. Despite these different means of identification, nerves contacts and intraneural injection are frequent. Even rare, nerve damage may occur. The nerve damage may be related to direct trauma with the needle or inadvertent intra-neural injection. High injection pressure of local anesthetic (AL) is an indicator that further characterize the location of the needle in terms of tissue density. In clinical practice, local anesthetic injection pressure monitoring is performed manually or by a pressure transducer according to the availability of the equipment or preferences of clinicians. To date, no comparative study has measured the advantages of this measure during PNB. The aim of this study is to evaluate injection pressure monitoring in order to reduce the risk of intraneural injection. Group 1: ultrasound-guided technique PNB in plane needle approach, nerve stimulator set to sentinel mode. Manual injection pressure control Group 2: ultrasound-guided PNB, in plane approach, Nerve stimulator set to detection mode. Electronic Injection Pressure controlled with low flow local anesthetic during procedure

Interventions

PROCEDUREManual measurement

Monitoring by ultrasound, Neurostimulation and Measurement Manual of the injection pressure of the local anesthetic

PROCEDUREMeasurement with a gauge

Monitoring by ultrasound, Neurostimulation and measurement with a gauge of the pressure of injection of the local anesthetic

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Adult patient * Orthopedic surgery

Exclusion criteria

* Allergy to local anesthetics * ASA score \>III * Severe neuropathy * puncture site disease * parturient or breastfeeding

Design outcomes

Primary

Measure	Time frame	Description
Manual measurement	Intraoperative	Manual measurement of the pressure of injection of the local anesthetic during surgery for patients in Group 1

Secondary

Measure	Time frame	Description
Measured by a pressure gauge	Intraoperative	Measured by a pressure gauge of the pressure of injection of the local anesthetic during surgery for patients in Group 2

Countries

France

Contacts

Primary ContactOlivier CHOQUET, MD

o-choquet@chu-montpellier.fr4 67 33 82 56

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026