Hip Fracture
Conditions
Brief summary
To determine if TXA utilization is effective at reducing transfusion rates in elderly patients undergoing surgery for treatment of a hip fractures.
Interventions
None listed
Sponsors
Corewell Health West
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Acute, isolated, unilateral femoral neck, intertrochanteric, and per trochanteric hip fractures confirmed by anteroposterior/lateral hip radiographs, computed tomography, or magnetic resonance imaging. * Age 65 and older * Low energy mechanism of injury * Hip fracture fixation performed within 48 hours * English speaking * Anticipated medical optimization for operative fixation * No other major trauma
Exclusion criteria
* Retained hardware around the affected hip * Infection around the affected hip * Transfer patients with a length of stay \> 24 hours at the transferring hospital * Diagnosis of deficient natural anticoagulation * Known congenital thrombophilia (Deficiency of Protein C, S, Antithrombin) * Known allergy to TXA * Patients undergoing percutaneous pinning of the hip fracture
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood Transfusion Rate | 6 weeks | Blood transfusion rates during the patients hospital stay will be assessed. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hospital Length of stay | 6 weeks | The patients length of stay in the hospital will be determined. |
| Post operative complications | 6 weeks | Post operative complications will be assessed through the 6 weeks. |
| Hospitalization costs | 6 weeks | Economic evaluation for inpatient and re-admission will be assessed. |
Outcome results
None listed