Meat Protein Supplements, Muscle Protein Synthesis, Protein Absorption and Amino Acid Availability
Conditions
Brief summary
To measure the absorption kinetics and postprandial amino acid availability after ingestion of minced beef compared with hydrolyzed beef in young males. Moreover, the basal muscle protein synthesis and the postprandial muscle protein synthetic response to minced beef and hydrolyzed beef ingestion are measured in young males. The postprandial muscle protein synthetic response is measured and compared during the early postprandial period (0-3 hours) after ingestion of the two meat products.
Interventions
Cow meat protein supplement
Cow meat protein supplement
Sponsors
Study design
Eligibility
Inclusion criteria
* Healthy * Non-obese (BMI\<30)
Exclusion criteria
* Chronic medical disease * \>5 hour of exercise weekly, except light activities such as stretching/gymnastics and bike-riding/walking as transportation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in skeletal muscle protein fractional synthetic rate | During the postprandial period (0-3 hrs). | The fractional synthetic rate of skeletal muscle proteins (%/h) measured during the overnight fasted state and the postprandial state. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Plasma amino acid concentration | During the postprandial period (0-3 hrs). | Change in venous plasma amino acid concentration after ingestion of meat protein. |
| Protein absorption | During the postprandial period (0-3 hrs). | The change in venous plasma ring-2H5-phenylalanine enrichment after ingestion of meat protein, reflects the protein absorption from the meat protein products. |
Countries
Denmark