Bronchiectasis
Conditions
Keywords
Bronchiectasis, Rehabilitation, Quality of Life, Physiotherapy Specialty
Brief summary
This study will investigate the short-and long-term effects of the home-based pulmonary rehabilitation on peripheral muscle strength, functional capacity and quality of life in patients with bronchiectasis. The participants will be randomized into two groups: control group (usual care and recommendations for practice exercise) and training group, that will perform aerobic (stepping training) and resistance training (lower and upper limbs) for eight weeks, three times a week. At baseline, immediately after finishing and after six months the patients will undergo assessments.
Detailed description
Home-based pulmonary rehabilitation (HBPR) has been used in patients with chronic obstructive pulmonary disease, asthma and pulmonary fibrosis. Results from HBPR have been similar to those observe in the outpatient pulmonary rehabilitation such improvement in exercise capacity, symptoms and quality of life. However, HBPR has not yet been investigated in patients with bronchiectasis, a progressive and debilitating disease with a high socioeconomic impact. Objective: To investigate the short-and long-term effects of the home rehabilitation program in peripheral muscle strength, functional capacity and quality of life in patients with bronchiectasis. Methods: Patients diagnosed with bronchiectasis will be recruited from the Obstructive Diseases Outpatient Clinic of the Hospital das Clínicas - Medicine School, University of São Paulo. Participants will be randomized into two groups: control group (usual care and recommendations for performing exercises and respiratory physiotherapy) and training group, that will perform aerobic (stepping training) and resistance training (lower and upper limbs) for eight weeks, three times a week. All patients will receive a phone call once a week and patients allocated to the training group, additionally, will get a home visit every 15 days. At baseline, immediately after finishing and after six months of the HBPR patients will undergo to assessments. Expected results: HBPR will have positive effects on exercise tolerance and quality of life. Also, this study will contribute to future guidelines on the recommendation of HBPR for patients with bronchiectasis.
Interventions
OTHERTraining Group
Three sessions per week, each lasting 50 minutes, during eight weeks. * Aerobic training in stepping training. * Resistance training: Three sets of eight repetitions each, in both simultaneous members, using an elastic band. The trained muscles are quadriceps, hamstrings, deltoid and biceps. * Once a week, patients will receive a phone call and every two weeks, patients will get a visit of the researcher at his home.
OTHERControl Group
* The participants will receive verbal and written information about the importance of physical activity and walk in moderate intensity, at least, three times a week for 30 minutes. * Participants will not receive any supervised physical training. * Once a week, patients will receive a phone call to provide support and general advice.
Sponsors
University of Sao Paulo
University of Nove de Julho
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Clinical diagnosis and/or tomographic bronchiectasis Clinically stable (no change in symptoms of dyspnea, in the amount and color of the secretion) Have completed the outpatient pulmonary rehabilitation for more than a year Not engaged in a regular physical activity.
Exclusion criteria
Smokers With other lung related diseases (asthma, COPD and cystic fibrosis) Severe cardiovascular diseases Musculoskeletal limitation Unable to perform the tests and the training protocol due desaturation (pulse oxygen saturation ≤ 80%) over the recommended exercise intensity.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Distance, in meters, performed in the Incremental Shuttle Walk Test | up to 9 months | Measurement of functional capacity and exercise tolerance |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time, in seconds, performed in the Endurance Shuttle Walk Test | up to 9 monthsst | Measurement of functional capacity and exercise tolerance |
| Number of steps performed in the Incremental Step Test | up to 9 months | Measurement of functional capacity and exercise tolerance |
| Physical functioning domain scale in the Quality of Life Questionnaire-Bronchiectasis (QoL-B) | up to 9 months | Quality of Life Questionnaire |
| Kilogram-force (kgf) of quadriceps femoris | up to 9 months | Peripheral Muscle Strength |
| Number of steps per day, measured by a pedometer | up to 9 months | Physical activity in daily life |
Countries
Brazil
Outcome results
None listed