Bowel Symptoms
Conditions
Brief summary
To study the prevalence of bowel symptoms in patients with pelvic organ prolapse.
Interventions
PROCEDUREPelvic floor reconstruction（with or without mesh）
Sponsors
Peking University People's Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* The patients with stage\>2 POP are recruited.The patients are all received surgeries, which include transvaginal synthetic mesh surgery, the sacral fixation, tissue repair surgery and colpocleisis.
Exclusion criteria
* Gestation； * Inflammatory bowel disease； * Slow transit constipation diagnosed by Colonic transit test； * Unable to follow up.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in the prevalence of bowel symptoms | baseline,1,3,6,12 months after operation. | — |
| change in the severity of intestinal symptoms | baseline,1,3,6,12 months after operation. | assessed by Birmingham Bowel and Urinary Symptoms Questionnaire |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change in the quality of life | baseline,1,3,6,12 months after operation. | assessed by international consultation on incontinence questionnaire short form |
| length of the high-pressure zone recorded by anorectal manometry | baseline and 12 months after operation | — |
| rectoanal inhibitory reflex recorded by anorectal manometry | baseline and 12 months after operation | — |
| Rectal-Vaginal pressure interval during maximum Vasalva | baseline and 6 months after operation | Measured by Peritron manometer |
Countries
China
Outcome results
None listed