Cardiac Diseases
Conditions
Keywords
Hemodynamics, Echocardiography, Doppler, Pulsed
Brief summary
The heart is essentially a hydraulic pump which ensures adequate delivery of blood through generating pressure and forward flow of blood. The energy delivered by the heart is uncommonly measured clinically, and todays gold standard involves placing a plastic catheter into the lung arteries. The investigators have developed an ultrasound based approach to calculate this energy without the need for catheters through the heart. This novel approach is called ultrapower. Ultrapower involves the instantaneous multiplication of the cardiac output and the arterial blood pressure. The study aims to use the ultrasound based approach to investigate Cardiac Power in the coronary artery bypass graft population.
Interventions
OTHERComparison cardiac power and cardiac power output at different time points in the perioperative period
The intervention is a comparison between two methods of calculating the heart's energy delivery, cardiac power, measured in watts. A tertiary measurement is calculation of arterioventricular coupling. All patients will have cardiac power output calculated through the use of Doppler echocardiography. The echocardiography based cardiac output will be done through the velocity time integral of the left ventricular outflow tract (LVOT). This will be compared against total power as measured by our Ultrapower approach which involves instantaneous doppler measurement of cardiac output through LVOT multiplied with simultaneous radial artery pressure. This and ejection fraction (for calculation of ventriculoarterial coupling) will be recorded at rest in neutral position preoperatively, directly post operatively and the day after operation. Directly postoperatively the power measurements will also be repeated in Trendelenburg and anti Trendelenburg position.
Sponsors
St. Olavs Hospital
Norwegian University of Science and Technology
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
• coronary artery bypass graft operation
Exclusion criteria
* Lack of informed consent * Previous aortic valve replacement * Inadequate Doppler signal on transthoracic echocardiography
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The hearts energy delivery per second measured in watts (Cardiac Power), using two established methods and the ultrapower method | Immediately preoperatively | Measured both as ultrapower and cardiac power output, both measured in watts and method of measurement described in intervention section |
Countries
Norway
Outcome results
None listed