Functional Dyspepsia
Conditions
Keywords
skin conductance response, facial muscle activity, heart rate variability, eyetracking
Brief summary
In functional dyspepsia (FD), abnormal cognitive and emotional changes such increased sensitization, anxiety, and depression scores have been reported in addition to the peripheral changes in gastrointestinal tract functions. In this study, investigators will evaluate the activity of autonomic nervous system, emotional response, and visual attention to food and non-food images in 30 male and female FD patients and 30 age/gender-matched healthy volunteers. These data will provide a new finding of the influence of impaired cognitive processing of food on symptom generation in functional gastrointestinal disorder patients.
Interventions
BEHAVIORALvisual images
Sponsors
University Hospital Tuebingen
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Male and female, volunteering adults BMI: 18-25 kg/m² right-handed Age: 18-65 years Capacity to give informed consent For FD patients, Diagnosis of functional dyspepsia over the last 12 months certified by a medical record Inconspicuous gastroscopy during the last 6 months certified by a medical record
Exclusion criteria
* Visual impairment Severe psychiatric illness (e.g. schizophrenia, severe depression (BDI-II:29-63)), substance dependence and abuse Intake of antidepressants / antipsychotics
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Psychological response | 1-2 years | Skin conductance response |
| visual attention | 1-2 years | eyemovement |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Subjective rating | 1-2 years | fullness (visual analog scale) |
Countries
Germany
Outcome results
None listed