Local Anesthesia
Conditions
Keywords
inferior alveolar nerve block, irreversible pulpitis, local anesthesia, sodium bicarbonate
Brief summary
The purpose of this prospective, randomized, double blind study was to evaluate the effect of a buccal infiltration of sodium bicarbonate on the anesthetic success of the inferior alveolar nerve block (IANB) in patients with mandibular first molar experiencing symptomatic
Detailed description
Several studies have been done by adding Sodium Bicarbonate to local anesthesia in dentistry based on the theory that the amount of local anesthetic in the free-base un-ionized form will decrease to provide greater lipid penetration of the nerve and this could be cause of the failure of local anesthesia injected into the inflamed tissue with low PH and conflicting results were obtained. But, there are no study that evaluate effect of increasing PH in periradicular tissue on hindrance of resistance channels with supplementary infiltration injection of Sodium Bicarbonate
Interventions
Sponsors
Masoud Saatchi
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* vital mandibular molar tooth * diagnosis of symptomatic irreversible pulpitis
Exclusion criteria
* younger than 18 years old * history of significant medical conditions * allergies to local anesthetics or sulfites * pregnancy * taking any medications that might influence anesthetic assessment * active sites of pathosis in area of injection * inability to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| success rate of IANB in the mandibular first molar with symptomatic irreversible pulpitis | Baseline |
Secondary
| Measure | Time frame |
|---|---|
| Heft-Parker visual analog scale recording of pain | Baseline |
Countries
Iran
Outcome results
None listed