Healthy
Conditions
Keywords
Performance
Brief summary
Compare a dietary supplement (PRJ-205) and placebo during 1 or 4 days on aerobic exercise performance, oxidative stress and muscle damage. The hypothesis is that supplementation with PRJ-205 improve aerobic performance
Detailed description
Twenty young active males will be recruited and randomized to either placebo or PRJ-205. Subjects will take the designated treatment in an acute dosage and chronically, 4 days of treatment. They will undergo 3 exercise tasks (before the administration of the product, 1.5h after the acute administration of the product and after 4 days of treatment). VO2max and anaerobic threshold will be measured during the tests. Blood samples will be taken to measure muscle damage and oxidative stress.
Interventions
DIETARY_SUPPLEMENTPRJ-205
1 sachet per day
OTHERPlacebo
1 sachet per day
Sponsors
University of Valencia
Bioiberica
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Male * Healthy * Physically active
Exclusion criteria
* known cardiovascular, pulmonary or metabolic disease * any medical condition that could affect the development and safety of the exercise task
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Aerobic performance determined by VO2max | 4 days |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pressure pain threshold of calf muscle | 4 days | Measured pre- and post- exercise task |
| Serum markers of muscular damage | 4 days | Measured from blood samples taken pre- and post- exercise task. |
| Oxidative stress parameters | 4 days | Measured from blood samples taken pre- and post- exercise task. |
Countries
Spain
Outcome results
None listed