Multiple Sclerosis, Endurance
Conditions
Brief summary
Objective: To compare effects of an intermittent and continuous walking program on walking endurance and fatigue in people with multiple sclerosis (MS).A randomized crossover prospective method was used.The intervention consisted of eight 6-minute-long walks (2x/week for 4 weeks). The continuous condition consisted of 6 continuous minutes of walking. The intermittent condition consisted of three 2-minute bouts with 2-minute rests. After a 4-week detraining period, participants performed the second training condition.
Interventions
Subjects walked either intermittently or continuously twice a week for 4 weeks, then crossed over
Sponsors
Study design
Eligibility
Inclusion criteria
* Positive diagnosis of MS * Ambulatory for at least 6 minutes with or without an assistive device (e.g. cane, crutches or orthotics) * Ability to read, understand, and sign an informed consent form
Exclusion criteria
* Evidence of exacerbation in the prior three months as defined by a treating physician * Orthopedic or cardiovascular condition that would interfere with ability to walk for 6 continuous minutes, * Currently being on an active physical rehabilitation program
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pre to post change in 6 Minute walk test distance | 4 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual Analog Scale of fatigue | 4 weeks | Measurements to be taken at baseline and after each 4 week intervention |