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Comparison of Intermittent vs. Continuous Walking in MS

The Effect of Intermittent vs. Continuous Walking Training on Walking Endurance and Fatigue in People With Multiple Sclerosis: a Randomized, Crossover Trial.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02726373
Enrollment
12
Registered
2016-04-01
Start date
2013-01-31
Completion date
2014-12-31
Last updated
2016-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis, Endurance

Brief summary

Objective: To compare effects of an intermittent and continuous walking program on walking endurance and fatigue in people with multiple sclerosis (MS).A randomized crossover prospective method was used.The intervention consisted of eight 6-minute-long walks (2x/week for 4 weeks). The continuous condition consisted of 6 continuous minutes of walking. The intermittent condition consisted of three 2-minute bouts with 2-minute rests. After a 4-week detraining period, participants performed the second training condition.

Interventions

OTHERtype of walking

Subjects walked either intermittently or continuously twice a week for 4 weeks, then crossed over

Sponsors

Hunter College of City University of New York
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Positive diagnosis of MS * Ambulatory for at least 6 minutes with or without an assistive device (e.g. cane, crutches or orthotics) * Ability to read, understand, and sign an informed consent form

Exclusion criteria

* Evidence of exacerbation in the prior three months as defined by a treating physician * Orthopedic or cardiovascular condition that would interfere with ability to walk for 6 continuous minutes, * Currently being on an active physical rehabilitation program

Design outcomes

Primary

MeasureTime frame
Pre to post change in 6 Minute walk test distance4 weeks

Secondary

MeasureTime frameDescription
Visual Analog Scale of fatigue4 weeksMeasurements to be taken at baseline and after each 4 week intervention

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026