Aortic Valve Disease
Conditions
Keywords
Automatic Data Processing, Three-Dimensional Echocardiography, Aortic Valve
Brief summary
The progress in surgery of the aortic root and the evolution of transcatheter aortic valve replacement as an alternative to surgical treatment in selected patients have refocused the need for quantitative imaging of the aortic root during transcatheter aortic valve replacement and valve-sparing aortic root surgery. In this study, we aim to assess the ability of semi-automated quantitative modeling (eSie Valves, Autovalve prototype version, Siemens Medical Solutions, USA) of the aortic valve and root in patients with clinical normal aortic valve and root, who are indicated for both 3D transesophageal echocardiography (TEE) and computed tomographic (CT) due to atrial fibrillation or patent foramen ovale. Measures of the aortic valve and root obtained by 2D TEE, 3D TEE and CT are compared, and the ability of the semi-automated 3D TEE modeling software is tested. Given the workflow advantages of automation, this 3D TEE approach may enhance the clinical adoption of routine 3-dimensional imaging beyond CT.
Detailed description
Recent developments in aortic root interventions have focused on the need for 3-dimensional imaging of the aortic functional anatomy. The progress in surgery of the aortic root and the evolution of transcatheter aortic valve replacement as an alternative to surgical treatment in selected patients have refocused the need for quantitative imaging of the aortic root during transcatheter aortic valve replacement and valve-sparing aortic root surgery. In this study, we aim to assess the ability of semi-automated quantitative modeling (eSie Valves, Autovalve prototype version, Siemens Medical Solutions, USA) of the aortic valve and root in patients with clinical normal aortic valve and root, who are indicated for both 3D transesophageal echocardiography (TEE) and computed tomographic (CT) due to atrial fibrillation or patent foramen ovale. Measures of the aortic valve and root obtained by 2D TEE, 3D TEE and CT are compared, and the ability of the semi-automated 3D TEE modeling software is tested. Given the workflow advantages of automation, this 3D TEE approach may enhance the clinical adoption of routine 3-dimensional imaging beyond CT.
Interventions
PROCEDUREThree-dimensional transoesophageal echocardiography
Three-dimensional transoesophageal echocardiography, analysed by eSie valve software (Siemens)
PROCEDUREComputed tomography
Computed tomography, analysed by Synovia Workstation (Siemens)
Sponsors
Siemens Corporation, Corporate Technology
Chinese Academy of Medical Sciences, Fuwai Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* both transesophageal echocardiography (TEE) and computed tomographic (CT) are referred by cardiologists * apparent normal aortic valve and root structure * written consent
Exclusion criteria
* post-operation of aortic valve * severe cardiomyopathy * cardiac functional insufficiency (NYHA III or IV) * contraindications for either TEE or cardiac CT angiography
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy | Through study completion, an average of 1 month | Compare semi-automatic assessment of 3D TEE to CT measurement |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cost | Through study completion, an average of 1 month | Compare cost between 3D TEE and CT |
| Labor time | Through study completion, an average of 1 month | Compare labor time between 3D TEE and CT |
Countries
China
Outcome results
None listed