Potential Associated Factors of Uncontrolled Hypertension

Initial Investigation on Potential Associated Factors of Uncontrolled Hypertension in Outpatient Department: A Prospective Registry Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02723643

Enrollment

2000

Registered

2016-03-30

Start date

2016-01-31

Completion date

Unknown

Last updated

2016-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension,Essential

Keywords

Hypertension, Essential hypertension, Blood pressure, Cardiovascular diseases

Brief summary

The incidence and prevalence of hypertension is increasing while the controlled rate is extremely low in China. A substantial percentage of participants with uncontrolled hypertension are correctable if potential associated factors are identified and corrected. Therefore, it is clinically relevant to investigate and identify these potential associated factors of uncontrolled hypertension so as to increase controlled rate and reduce hypertension-associated health and economic burdens in the future. Investigators plan to conduct a prospective registry study in a single-center to initially investigate the potential associated factors of uncontrolled hypertension in cardiovascular outpatient department. Furthermore, investigators plan to evaluate the effects of potential associated factors correction on hypertension controlled rate and cardiovascular outcomes.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

50 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Clinic systolic and/or diastolic blood pressure above 140 and/or 90 mm Hg treating with 3 different classes of anti-hypertensive drugs (not necessarily including diuretic).

Exclusion criteria

* Known secondary hypertension, * Pregnant women, * Chronic kidney disease (CKD) 3 or higher, * Has a history of connective tissue diseases, * Has a history of any type of cancer, * Cognitive disorder which could not finish home blood pressure monitoring, * Has a history of coronary heart disease,ischemic stroke,transient ischemic attack or heart failure.

Design outcomes

Primary

Measure	Time frame	Description
Hypertension controlled rate in participants after potential associated factors are corrected	Up to 1 month	Participants with uncontrolled hypertension (SBP and/or DBP \>=140 and/or 90 mm Hg) treating with 3 or more anti-hypertensive drugs (not necessarily including diuretic) in outpatient department will under assessment of hypertension controlled rate 1 month later after initial investigation of potential associated factors. Based on these findings, investigators will give instructions to participants how to correct those potential associated factors and follow-up participants via telephone or outpatient visit 1 month later to assess whether these corrections could help increase hypertension controlled rate. Participants will be required to record home blood pressure measurements every day, and average home SBP and DBP will be calculated 1 month later. If average home SBP/DBP \< 135/85 mm Hg then participants will be considered as controlled-case, otherwise uncontrolled case.

Countries

China

Contacts

Primary ContactAnping Cai, MD

caianping1983@hotmail.com8615989267312

Outcome results