Diabetes Mellitus
Conditions
Keywords
Pediatrics
Brief summary
The aim of this study is the identification of complications in diabetes mellitus pediatric patients and to compare the clinical, anthropometric, and biochemical characteristics between children in the different types of diabetes mellitus.
Detailed description
Diabetes mellitus is characterized by hyperglycemia resulting from defects in insulin secretion and/or insulin resistance in target tissues. This study identify the influence of pathogenic factors on the evolution of diabetes mellitus and in the presence of chronic complications.
Interventions
None listed
Sponsors
Hospital Regional de Alta Especialidad del Bajio
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Months to 17 Years
Healthy volunteers
No
Inclusion criteria
* Patients with confirmed diagnosis of diabetes mellitus
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cognitive evaluation | year 3 | Determined by scores on the Mini-Mental State Examination |
| Intelligence quotient evaluation | year 3 | Determined by Intelligence quotient test |
| Diabetic retinopathy | year 3 | A microvascular complication determined by ophthalmological evaluation |
| Peripheral diabetic neuropathy | year 5 | A microvascular complication determined by neurological exam in either foot |
| Nerve damage | year 5 | A microvascular complication determined by nerve conduction study in either foot |
| Microalbuminuria | annual | A microvascular complication determined by urine albumin excretion \>= 30 mg/day |
| Cardiac function | year 5 | A cardiovascular risk indicator determined by echocardiogram |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hypothyroidism | annual | Determined by thyroid profile |
| Body composition | annual | Determined by body mass index (BMI) percentiles computed from physical measurements of height and weight and corresponding percentile tables |
| Hypertension | annual | Determined by collection of systolic and diastolic blood pressure and calculation of their percentile values |
| Glycemic control | annual | Determined by HbA1c |
| Beta cell function | annual | Determined by fasting C peptide |
| Pancreatic autoimmunity | onset of diabetes | Determined by pancreas autoantibodies |
| Insulin resistance | annual | Determined by insulin sensitivity |
| Alpha cell function | year 5 | Determined by glucagon |
| Hyperlipidemia | annual | Determined by lipid profile |
Countries
Mexico
Contacts
Primary ContactMaría L Evia-Viscarra
Outcome results
None listed