Omega-3 Fatty Acids Enriched Food and Microvascular Reactivity

Effect of Omega-3 Fatty Acids Enriched Chicken Eggs Consumption on Microvascular Reactivity and Lipid Profile in Young Healthy Subjects

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02720250

Enrollment

Registered

2016-03-25

Start date

2016-03-31

Completion date

2018-12-31

Last updated

2016-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Omega-3 Polyunsaturated Fatty Acids

Keywords

omega-3 fatty acids, microcirculation, laser Doppler flowmetry, lipid profile

Brief summary

Previous studies have shown that omega-3 fatty acid pills intake have beneficial effect on vascular health in overweight and/or hypertensive patients. However, there is a lack of studies showing the effect of everyday consumption of omega-3 fatty acids enriched food (not pills) on lipid profile and microvascular reactivity in healthy population. This study aimed to determine the effect of omega-3 enriched chicken eggs consumption on microvascular reactivity and lipid profile in young healthy subjects.

Interventions

DIETARY_SUPPLEMENTOmega-3 chicken eggs

Intake of 3 omega-3 fatty acids enriched chicken eggs per day for three weeks.

DIETARY_SUPPLEMENTRegular chicken eggs

Intake of 3 regular chicken eggs per day for three weeks.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

\- healthy volunteers

Exclusion criteria

* oral contraceptives * drugs that could affect endothelium * hypertension * coronary artery disease * diabetes * hyperlipidaemia * renal impairment * cerebrovascular and peripheral artery disease

Design outcomes

Primary

Measure	Time frame	Description
microvascular reactivity	Three weeks	Cutaneous microvascular blood flow will be measured by Laser Doppler Flowmetry in response to vascular occlusion (post occlusive reactive hyperaemia - PORH) and in response to iontophoresis of acetylcholine (ACh) (endothelium dependent vasodilation).

Secondary

Measure	Time frame	Description
lipid profile	Three weeks	Measurement of plasma cholesterol, HDL cholesterol, LDL cholesterol and triglycerides level.

Countries

Croatia

Contacts

Primary ContactAna Stupin, MD, PhD

anacavka@mefos.hr+385915134958

Backup ContactInes Drenjancevic, MD, PhD

ines.drenjancevic@mefos.hr+385912241406

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026