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Cognitive-Behavioral Conjoint Therapy (CBCT) Project

An Integrative Technology Approach to Home-based Conjoint Therapy for PTSD

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02720016
Acronym
CBCT
Enrollment
274
Registered
2016-03-25
Start date
2016-10-03
Completion date
2021-03-31
Last updated
2022-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Traumatic Stress Disorder

Keywords

Post Traumatic Stress Disorder, Marital Therapy, Veterans, Telemedicine, Couples

Brief summary

Untreated posttraumatic stress disorder (PTSD) is a costly condition associated with impairment in functioning across a host of psychosocial domains including occupational and academic functioning, marital and family functioning, parenting, and socialization. Impairment is not limited to Veterans with PTSD because the entire family is affected, particularly the Veteran's intimate partner. PTSD symptoms can produce negative effects on both members of the dyad. Despite the need for treatment, many Veterans and their families do not access PTSD-related services due to a number of barriers to accessing care (e.g., living in rural or remote areas where no specialty services exist, concerns about stigma around using mental health services, limited clinic hours to accommodate patient schedules). The objective of this study is to assess whether providing Cognitive-Behavioral Conjoint Therapy, in which PTSD symptoms and intimate relationship functioning are addressed, to Veterans and their romantic partners in their homes via clinical video teleconferencing leads to better outcomes compared to office based treatment.

Detailed description

Anticipated Impact on Veterans' Healthcare: This project addresses the mental health and functioning needs of Veterans and their families by increasing the access to an established treatment using telemental health technology. Project Background: Veterans and their families experience the deleterious effects of posttraumatic stress disorder (PTSD) and associated negative sequelae. PTSD is related to a variety of comorbid mental health symptomatology and psychosocial impairment, including high rates of intimate relationship problems which impact Veterans' recovery and functioning. Despite available couple-based interventions, barriers to care such as stigma regarding mental health treatment, travel time to receive care, and transportation costs, make it difficult for Veterans and their families to access specialty PTSD treatments necessary for rehabilitation. Home-based clinical video teleconferencing (CVT) delivers specialized mental health treatments to clients in the ease of their own home, which allows clinicians to directly observe the client's home environment and family milieu. Cognitive-Behavioral Conjoint Therapy (CBCT), a couple-based treatment designed to target PTSD symptoms and improve individual and relationship functioning, has shown evidence of improvements in clinical symptom outcomes in research conducted with Veterans and their partners. Project Objectives: This is a 4-year randomized controlled trial. The primary objective of this study is to compare the clinical efficacy (PTSD symptoms, relationship distress, and functional impairment) of CBCT delivered via an office-based (CBCT-OB) or a home-based CVT (CBCT-HB) delivery modality to the PTSD Family Education control condition (PFE). In addition, this study will estimate and compare the difference in clinical efficacy between CBCT delivered via an office-based (CBCT-OB) or a home-based CVT (CBCT-HB) delivery modality if indicated by results of the primary objective. This study will also compare process outcomes (therapeutic alliance, enrollment and dropout rates, and treatment satisfaction) for CBCT-OB, CBCT-HB, and PFE. Project Methods: Participants will be 180 intent-to-treat couples in which one partner is a PTSD-positive Veteran. Couples will be randomly assigned to receive treatment through one of the three treatment delivery modalities: CBCT-OB, CBCT-HB or PFE. Assessments will be conducted at baseline, mid- and post-treatment, and 3- and 6-months post-treatment. The primary outcome variables of clinical efficacy will be measures of PTSD symptom severity, relationship distress, and functional impairment. Secondary outcome variables include PTSD diagnostic status, self- reported PTSD symptoms, depression, anger, and relationship conflict. Additionally, primary process outcomes will include measures of treatment retention, attendance, therapeutic alliance, and treatment satisfaction. Variability in scores for each of the primary and secondary outcome measures will be examined individually in a series of separate multilevel models. The results will provide evidence that can be used to further increase the clinical efficacy, ease of access to, and utilization of specialty PTSD treatment to Veterans and their families.

Interventions

BEHAVIORALCBCT-Home Based (CBCT-HB)

Couples in CBCT-HB will receive 8 sessions of standardized Cognitive-Behavioral Conjoint Therapy (CBCT), a manualized couple-based intervention for PTSD designed to simultaneously reduce PTSD and enhance relationship and functioning. The psychotherapy is administered over 8 to 15 weeks to the Veterans home via home-based clinical video teleconferencing (CVT).

BEHAVIORALCBCT-Office Based (CBCT-OB)

Couples in CBCT-OB will receive 8 sessions of standardized Cognitive-Behavioral Conjoint Therapy (CBCT), a manualized couple-based intervention for PTSD designed to simultaneously reduce PTSD and enhance relationship and functioning. The psychotherapy is administered over 8 to 15 weeks in-person in the therapist's office.

BEHAVIORALPTSD Family Education (PFE)

Couples in the PFE condition will receive 8 sessions of standardized PTSD Family Education, a manualized psychoeducational program designed to help couples learn more about posttraumatic stress disorder and related difficulties. This psychotherapy is administered over 8 to 15 weeks and is delivered in-person in the therapist's office.

Sponsors

VA Office of Research and Development
Lead SponsorFED

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Masking description

Study assessors are kept blind to the couple's randomly assigned treatment condition.

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Be a Veteran (age 18 or older) with a current Diagnostic and Statistical Manual-5 (DSM-5) diagnosis of PTSD (as assessed by the CAPS) no less than 3 months after the index trauma occurred (to allow for potential natural recovery) * Be on a stable psychoactive medication regimen for at least 2 months (if eligible) * Be an intimate partner (age 18 or older) who is willing to participate in the intervention. * Be randomized into any of the three treatment conditions * Have assessment and treatment sessions audio recorded * Agree not to receive other individual or conjoint psychotherapy for PTSD during the treatment portion of the study * Consistent with home-based clinical trials and actual clinical practice * Participants enrolled into the study will need to have access to internet via Digital Subscriber Line (DSL) or a cable provider in case they are randomized into the home-based condition. * The frequency of occurrence of no internet service will be tracked * If the PTSD-positive Veteran is currently receiving treatment at the VA, study staff will consult with their primary clinician prior to their inclusion in the study

Exclusion criteria

* Current substance dependence in either member of the couple not in remission for at least 3 months, as assessed by the Alcohol Use Disorders Identification Test (AUDIT)108 and Drug Abuse Screening Test (DAST) * Any current uncontrolled psychotic disorder in either member of the couple * Imminent suicidality or homicidality in either member of the couple * Any severe cognitive impairment in either member of the couple * Any perpetration of severe physical or sexual relationship aggression in the past year (as assessed by the Conflict Tactics Scale-2 \[CTS-2\]). * Participants who do not meet study criteria will be offered referrals to alternate services, as well as assistance in contacting the referral sites as needed

Design outcomes

Primary

MeasureTime frameDescription
Working Alliance Inventory- Short Form (WAI-S)Approximately week 3 of all treatment conditionsThis adaptation of the Working Alliance Inventory- short form (WAI-S) includes 14 items assessing therapeutic alliance as reported by the patient on a 7-point Likert scale. Higher sum scores (14 to 98) represent higher patient-reported working alliance.
Clinician Administered PTSD Scale (CAPS)BaselineThe CAPS-5 is a 30-item clinician administered interview designed to diagnose current and lifetime PTSD and to assess PTSD symptom-severity over the past week. The interview assesses 20 DSM-5 PTSD symptoms as well as onset, duration, distress, and functional impact, overall validity, PTSD severity, and presence of dissociation. Prior to assessing symptoms, the clinical interviewer works with the patient to establish an index-trauma and each follow-up question focuses on symptoms as they relate to the index trauma. \*Score range: 0-80 with higher score indicating greater symptom severity
Couples Satisfaction Index (CSI)BaselineThe Couples Satisfaction Index is a 32-item self-report survey assessing several domains of relationship satisfaction. Higher sum scores (range 0 to 161) represent higher relationship satisfaction.
Inventory of Psychosocial Functioning (IPF)BaselineThe Inventory of Psychosocial Functioning (IPF) is an 80-item self-report measure designed to assess multiple dimensions of functional impairment related to psychiatric disturbances. Higher sum scores (range 0 to 100) indicate more functional impairment.
Client Satisfaction Questionnaire (CSQ)1 Month Post TreatmentClient Satisfaction Questionnaire (CSQ) is an 8-item measure about satisfaction with treatment rated on a 4-point Likert scale. Higher mean scores (range 0 to 4) represent higher satisfaction with treatment services.

Secondary

MeasureTime frameDescription
Beck Depression Inventory-II (BDI-2)BaselineThe BDI is a 21-item self report questionnaire assessing symptoms of depression. Scores range from 0 to 63, with higher scores representing more severe symptoms.
State-Trait Anger Inventory (STAXI)BaselineThe STAXI-2 is a self-report questionnaire assessing state and trait anger. The State subscale (15 items) ranges from 15 to 60, and the Trait subscale (10 items) ranges from 10 to 40, with higher scores representing more anger.
Conflict Tactics Scale Short Form- (CTS-2S)Baseline20-item self-report inventory yielding 5 scales. Most widely used measure of its kind. Scores on the Psychological Aggression and Negotiation subscales range from 0 to 24, with higher scores representing more Psychological Aggression and more Negotiation.
PTSD Checklist-5 (PCL-5)BaselineThe PCL-5 is a 20 item self report questionnaire assessing symptoms of PTSD based on DSM-V criteria. Scores range from 0 to 80, with higher scores representing more severe symptoms.

Countries

United States

Participant flow

Recruitment details

During the recruitment period from October 2016 to March 2020, we received 706 referrals from the myriad of community-based outpatient clinics (CBOCs; e.g., VA Mission Valley Clinic), VA associated clinics (e.g., Family Mental Health), and self-referrals, typically from Veterans who see our study ads (both virtual and physical) in the La Jolla VA Main Hospital.

Participants by arm

ArmCount
CBCT-Home Based (CBCT-HB)
Couples in CBCT-HB will receive 8 sessions of standardized Cognitive-Behavioral Conjoint Therapy (CBCT), a manualized couple-based intervention for PTSD designed to simultaneously reduce PTSD and enhance relationship and functioning. The psychotherapy is administered over 8 to 15 weeks to the Veterans home via home-based clinical video teleconferencing (CVT). CBCT-Home Based (CBCT-HB): Couples in CBCT-HB will receive 8 sessions of standardized Cognitive-Behavioral Conjoint Therapy (CBCT), a manualized couple-based intervention for PTSD designed to simultaneously reduce PTSD and enhance relationship and functioning. The psychotherapy is administered over 8 to 15 weeks to the Veterans home via home-based clinical video teleconferencing (CVT).
92
CBCT-Office Based (CBCT-OB)
Couples in CBCT-OB will receive 8 sessions of standardized Cognitive-Behavioral Conjoint Therapy (CBCT), a manualized couple-based intervention for PTSD designed to simultaneously reduce PTSD and enhance relationship and functioning. The psychotherapy is administered over 8 to 15 weeks in-person in the therapist's office. CBCT-Office Based (CBCT-OB): Couples in CBCT-OB will receive 8 sessions of standardized Cognitive-Behavioral Conjoint Therapy (CBCT), a manualized couple-based intervention for PTSD designed to simultaneously reduce PTSD and enhance relationship and functioning. The psychotherapy is administered over 8 to 15 weeks in-person in the therapist's office.
92
PTSD Family Education (PFE)
Couples in the PFE condition will receive 8 sessions of standardized PTSD Family Education, a manualized psychoeducational program designed to help couples learn more about posttraumatic stress disorder and related difficulties. This psychotherapy is administered over 8 to 15 weeks and is delivered in-person in the therapist's office. PTSD Family Education (PFE): Couples in the PFE condition will receive 8 sessions of standardized PTSD Family Education, a manualized psychoeducational program designed to help couples learn more about posttraumatic stress disorder and related difficulties. This psychotherapy is administered over 8 to 15 weeks and is delivered in-person in the therapist?s office.
90
Total274

Withdrawals & dropouts

PeriodReasonFG000FG001FG002
Overall StudyChildcare202
Overall StudyMoved away200
Overall StudyNot Primary Health Concern002
Overall StudyOther002
Overall StudyScheduling issues247
Overall StudySeparation of couple682
Overall StudyTransportation issues001
Overall StudyWithdrawal by PI220
Overall StudyWithdrawal by Subject664

Baseline characteristics

CharacteristicCBCT-Home Based (CBCT-HB)CBCT-Office Based (CBCT-OB)PTSD Family Education (PFE)Total
Age, Categorical
<=18 years
0 Participants0 Participants0 Participants0 Participants
Age, Categorical
>=65 years
7 Participants5 Participants14 Participants26 Participants
Age, Categorical
Between 18 and 65 years
85 Participants87 Participants76 Participants248 Participants
Age, Continuous42.37 years
STANDARD_DEVIATION 12.42
39.25 years
STANDARD_DEVIATION 12.45
43.89 years
STANDARD_DEVIATION 15.24
41.82 years
STANDARD_DEVIATION 13.51
B-IPF42.0 units on a scale
STANDARD_DEVIATION 21.5
41.6 units on a scale
STANDARD_DEVIATION 21.8
39.8 units on a scale
STANDARD_DEVIATION 19.3
41.1 units on a scale
STANDARD_DEVIATION 20.8
CAPS-538.5 units on a scale
STANDARD_DEVIATION 9.35
37.2 units on a scale
STANDARD_DEVIATION 9.95
36.9 units on a scale
STANDARD_DEVIATION 9.14
37.5 units on a scale
STANDARD_DEVIATION 9.44
CSI102.9 units on a scale
STANDARD_DEVIATION 31.4
104.8 units on a scale
STANDARD_DEVIATION 35.9
111.9 units on a scale
STANDARD_DEVIATION 30
106.4 units on a scale
STANDARD_DEVIATION 32.7
Ethnicity (NIH/OMB)
Hispanic or Latino
31 Participants33 Participants29 Participants93 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
60 Participants58 Participants58 Participants176 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
1 Participants1 Participants3 Participants5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
3 Participants2 Participants2 Participants7 Participants
Race (NIH/OMB)
Asian
5 Participants2 Participants7 Participants14 Participants
Race (NIH/OMB)
Black or African American
13 Participants21 Participants12 Participants46 Participants
Race (NIH/OMB)
More than one race
0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
5 Participants3 Participants1 Participants9 Participants
Race (NIH/OMB)
Unknown or Not Reported
16 Participants18 Participants15 Participants49 Participants
Race (NIH/OMB)
White
50 Participants46 Participants53 Participants149 Participants
Sex: Female, Male
Female
46 Participants46 Participants45 Participants137 Participants
Sex: Female, Male
Male
46 Participants46 Participants45 Participants137 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
EG002
affected / at risk
deaths
Total, all-cause mortality
0 / 920 / 920 / 90
other
Total, other adverse events
8 / 9214 / 9214 / 90
serious
Total, serious adverse events
0 / 920 / 920 / 92

Outcome results

Primary

Client Satisfaction Questionnaire (CSQ)

Client Satisfaction Questionnaire (CSQ) is an 8-item measure about satisfaction with treatment rated on a 4-point Likert scale. Higher mean scores (range 0 to 4) represent higher satisfaction with treatment services.

Time frame: 1 Month Post Treatment

Population: Entire enrolled sample, both partners; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Client Satisfaction Questionnaire (CSQ)3.389157 score on a scaleStandard Error 0.1080726
CBCT-Office Based (CBCT-OB)Client Satisfaction Questionnaire (CSQ)3.423814 score on a scaleStandard Error 0.1029292
PTSD Family Education (PFE)Client Satisfaction Questionnaire (CSQ)3.421993 score on a scaleStandard Error 0.1092805
Primary

Clinician Administered PTSD Scale (CAPS)

The CAPS-5 is a 30-item clinician administered interview designed to diagnose current and lifetime PTSD and to assess PTSD symptom-severity over the past week. The interview assesses 20 DSM-5 PTSD symptoms as well as onset, duration, distress, and functional impact, overall validity, PTSD severity, and presence of dissociation. Prior to assessing symptoms, the clinical interviewer works with the patient to establish an index-trauma and each follow-up question focuses on symptoms as they relate to the index trauma. \*Score range: 0-80 with higher score indicating greater symptom severity

Time frame: 3-Months Post Treatment

Population: Entire enrolled sample, Veteran partners only; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Clinician Administered PTSD Scale (CAPS)24.483465 score on a scaleStandard Error 2.2550249
CBCT-Office Based (CBCT-OB)Clinician Administered PTSD Scale (CAPS)24.647374 score on a scaleStandard Error 2.2486121
PTSD Family Education (PFE)Clinician Administered PTSD Scale (CAPS)30.361910 score on a scaleStandard Error 2.2410544
Primary

Clinician Administered PTSD Scale (CAPS)

The CAPS-5 is a 30-item clinician administered interview designed to diagnose current and lifetime PTSD and to assess PTSD symptom-severity over the past week. The interview assesses 20 DSM-5 PTSD symptoms as well as onset, duration, distress, and functional impact, overall validity, PTSD severity, and presence of dissociation. Prior to assessing symptoms, the clinical interviewer works with the patient to establish an index-trauma and each follow-up question focuses on symptoms as they relate to the index trauma. \*Score range: 0-80 with higher score indicating greater symptom severity

Time frame: 6- Months Post Treatment

Population: Entire enrolled sample, Veteran partners only; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Clinician Administered PTSD Scale (CAPS)25.225243 score on a scaleStandard Error 2.3268567
CBCT-Office Based (CBCT-OB)Clinician Administered PTSD Scale (CAPS)24.869300 score on a scaleStandard Error 2.3450681
PTSD Family Education (PFE)Clinician Administered PTSD Scale (CAPS)28.281612 score on a scaleStandard Error 2.2157577
Primary

Clinician Administered PTSD Scale (CAPS)

The CAPS-5 is a 30-item clinician administered interview designed to diagnose current and lifetime PTSD and to assess PTSD symptom-severity over the past week. The interview assesses 20 DSM-5 PTSD symptoms as well as onset, duration, distress, and functional impact, overall validity, PTSD severity, and presence of dissociation. Prior to assessing symptoms, the clinical interviewer works with the patient to establish an index-trauma and each follow-up question focuses on symptoms as they relate to the index trauma. \*Score range: 0-80 with higher score indicating greater symptom severity

Time frame: 1 Month Post Treatment

Population: Entire enrolled sample, Veteran partners only; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Clinician Administered PTSD Scale (CAPS)25.400853 score on a scaleStandard Error 2.091249
CBCT-Office Based (CBCT-OB)Clinician Administered PTSD Scale (CAPS)25.949376 score on a scaleStandard Error 2.0622709
PTSD Family Education (PFE)Clinician Administered PTSD Scale (CAPS)31.697835 score on a scaleStandard Error 2.0545996
Comparison: Analyses were pooled across 50 imputed data sets. We used piecewise/spline mixed-effects regression models: one slope estimated from baseline to post (treatment impacts), with a separate slope estimated from post to 6-months (maintenance).p-value: 0.016Mixed-effects regression
Comparison: Analyses were pooled across 50 imputed data sets. We used piecewise/spline mixed-effects regression models: one slope estimated from baseline to post (treatment impacts), with a separate slope estimated from post to 6-months (maintenance).p-value: 0.002Mixed-effects regression
Comparison: Analyses were pooled across 50 imputed data sets. We used piecewise/spline mixed-effects regression models: one slope estimated from baseline to post (treatment impacts), with a separate slope estimated from post to 6-months (maintenance).p-value: 0.492Mixed-effects regression
Primary

Clinician Administered PTSD Scale (CAPS)

The CAPS-5 is a 30-item clinician administered interview designed to diagnose current and lifetime PTSD and to assess PTSD symptom-severity over the past week. The interview assesses 20 DSM-5 PTSD symptoms as well as onset, duration, distress, and functional impact, overall validity, PTSD severity, and presence of dissociation. Prior to assessing symptoms, the clinical interviewer works with the patient to establish an index-trauma and each follow-up question focuses on symptoms as they relate to the index trauma. \*Score range: 0-80 with higher score indicating greater symptom severity

Time frame: Baseline

Population: Entire enrolled sample, Veteran partners only; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Clinician Administered PTSD Scale (CAPS)38.456522 score on a scaleStandard Error 1.379178
CBCT-Office Based (CBCT-OB)Clinician Administered PTSD Scale (CAPS)37.239130 score on a scaleStandard Error 1.4665958
PTSD Family Education (PFE)Clinician Administered PTSD Scale (CAPS)36.933333 score on a scaleStandard Error 1.3627068
Primary

Couples Satisfaction Index (CSI)

The Couples Satisfaction Index is a 32-item self-report survey assessing several domains of relationship satisfaction. Higher sum scores (range 0 to 161) represent higher relationship satisfaction.

Time frame: 6- Months Post Treatment

Population: Entire enrolled sample, both partners; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Couples Satisfaction Index (CSI)109.384934 score on a scaleStandard Error 4.1233647
CBCT-Office Based (CBCT-OB)Couples Satisfaction Index (CSI)110.919753 score on a scaleStandard Error 4.7608962
PTSD Family Education (PFE)Couples Satisfaction Index (CSI)118.410443 score on a scaleStandard Error 3.9590245
Primary

Couples Satisfaction Index (CSI)

The Couples Satisfaction Index is a 32-item self-report survey assessing several domains of relationship satisfaction. Higher sum scores (range 0 to 161) represent higher relationship satisfaction.

Time frame: Baseline

Population: Entire enrolled sample, both partners; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Couples Satisfaction Index (CSI)102.936782 score on a scaleStandard Error 3.3421657
CBCT-Office Based (CBCT-OB)Couples Satisfaction Index (CSI)104.847826 score on a scaleStandard Error 3.7405059
PTSD Family Education (PFE)Couples Satisfaction Index (CSI)112.168689 score on a scaleStandard Error 3.2376775
Primary

Couples Satisfaction Index (CSI)

The Couples Satisfaction Index is a 32-item self-report survey assessing several domains of relationship satisfaction. Higher sum scores (range 0 to 161) represent higher relationship satisfaction.

Time frame: Mid Treatment (Approximately week 5 of all treatment conditions)

Population: Entire enrolled sample, both partners; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Couples Satisfaction Index (CSI)103.004524 score on a scaleStandard Error 3.8251803
CBCT-Office Based (CBCT-OB)Couples Satisfaction Index (CSI)108.112456 score on a scaleStandard Error 4.1797505
PTSD Family Education (PFE)Couples Satisfaction Index (CSI)114.748458 score on a scaleStandard Error 3.5772543
Primary

Couples Satisfaction Index (CSI)

The Couples Satisfaction Index is a 32-item self-report survey assessing several domains of relationship satisfaction. Higher sum scores (range 0 to 161) represent higher relationship satisfaction.

Time frame: 1 Month Post Treatment

Population: Entire enrolled sample, both partners; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Couples Satisfaction Index (CSI)109.481289 score on a scaleStandard Error 4.1068688
CBCT-Office Based (CBCT-OB)Couples Satisfaction Index (CSI)112.741213 score on a scaleStandard Error 4.3721817
PTSD Family Education (PFE)Couples Satisfaction Index (CSI)120.408861 score on a scaleStandard Error 3.5479556
Comparison: Analyses were pooled across 50 imputed data sets. We used piecewise/spline mixed-effects regression models: one slope estimated from baseline to post (treatment impacts), with a separate slope estimated from post to 6-months (maintenance).p-value: 0.872Mixed-effects regression
Comparison: Analyses were pooled across 50 imputed data sets. We used piecewise/spline mixed-effects regression models: one slope estimated from baseline to post (treatment impacts), with a separate slope estimated from post to 6-months (maintenance).p-value: 0.686Mixed-effects regression
Comparison: Analyses were pooled across 50 imputed data sets. We used piecewise/spline mixed-effects regression models: one slope estimated from baseline to post (treatment impacts), with a separate slope estimated from post to 6-months (maintenance).p-value: 0.798Mixed-effects regression
Primary

Couples Satisfaction Index (CSI)

The Couples Satisfaction Index is a 32-item self-report survey assessing several domains of relationship satisfaction. Higher sum scores (range 0 to 161) represent higher relationship satisfaction.

Time frame: 3- Months Post Treatment

Population: Entire enrolled sample, both partners; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Couples Satisfaction Index (CSI)108.873270 score on a scaleStandard Error 4.3020165
CBCT-Office Based (CBCT-OB)Couples Satisfaction Index (CSI)111.135788 score on a scaleStandard Error 4.8525214
PTSD Family Education (PFE)Couples Satisfaction Index (CSI)119.612750 score on a scaleStandard Error 3.8630495
Primary

Inventory of Psychosocial Functioning (IPF)

The Inventory of Psychosocial Functioning (IPF) is an 80-item self-report measure designed to assess multiple dimensions of functional impairment related to psychiatric disturbances. Higher sum scores (range 0 to 100) indicate more functional impairment.

Time frame: Mid Treatment (Approximately week 5 of all treatment conditions)

Population: Entire enrolled sample, Veteran partners only; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Inventory of Psychosocial Functioning (IPF)43.4390 score on a scaleStandard Error 3.79594
CBCT-Office Based (CBCT-OB)Inventory of Psychosocial Functioning (IPF)43.0393 score on a scaleStandard Error 3.68072
PTSD Family Education (PFE)Inventory of Psychosocial Functioning (IPF)44.8664 score on a scaleStandard Error 3.95252
Primary

Inventory of Psychosocial Functioning (IPF)

The Inventory of Psychosocial Functioning (IPF) is an 80-item self-report measure designed to assess multiple dimensions of functional impairment related to psychiatric disturbances. Higher sum scores (range 0 to 100) indicate more functional impairment.

Time frame: 1 Month Post Treatment

Population: Entire enrolled sample, Veteran partners only; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Inventory of Psychosocial Functioning (IPF)33.2541 score on a scaleStandard Error 4.09738
CBCT-Office Based (CBCT-OB)Inventory of Psychosocial Functioning (IPF)33.9657 score on a scaleStandard Error 3.82502
PTSD Family Education (PFE)Inventory of Psychosocial Functioning (IPF)34.0572 score on a scaleStandard Error 3.8824
Comparison: Analyses were pooled across 50 imputed data sets. We used piecewise/spline mixed-effects regression models: one slope estimated from baseline to post (treatment impacts), with a separate slope estimated from post to 6-months (maintenance).p-value: 0.631Mixed-effects regression
Comparison: Analyses were pooled across 50 imputed data sets. We used piecewise/spline mixed-effects regression models: one slope estimated from baseline to post (treatment impacts), with a separate slope estimated from post to 6-months (maintenance).p-value: 0.56Mixed-effects regression
Comparison: Analyses were pooled across 50 imputed data sets. We used piecewise/spline mixed-effects regression models: one slope estimated from baseline to post (treatment impacts), with a separate slope estimated from post to 6-months (maintenance).p-value: 0.922Mixed-effects regression
Primary

Inventory of Psychosocial Functioning (IPF)

The Inventory of Psychosocial Functioning (IPF) is an 80-item self-report measure designed to assess multiple dimensions of functional impairment related to psychiatric disturbances. Higher sum scores (range 0 to 100) indicate more functional impairment.

Time frame: 3- Months Post Treatment

Population: Entire enrolled sample, Veteran partners only; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Inventory of Psychosocial Functioning (IPF)35.6696 score on a scaleStandard Error 4.15061
CBCT-Office Based (CBCT-OB)Inventory of Psychosocial Functioning (IPF)33.6290 score on a scaleStandard Error 4.3715
PTSD Family Education (PFE)Inventory of Psychosocial Functioning (IPF)34.5942 score on a scaleStandard Error 4.08413
Primary

Inventory of Psychosocial Functioning (IPF)

The Inventory of Psychosocial Functioning (IPF) is an 80-item self-report measure designed to assess multiple dimensions of functional impairment related to psychiatric disturbances. Higher sum scores (range 0 to 100) indicate more functional impairment.

Time frame: 6- Months Post Treatment

Population: Entire enrolled sample, Veteran partners only; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Inventory of Psychosocial Functioning (IPF)38.3285 score on a scaleStandard Error 4.15604
CBCT-Office Based (CBCT-OB)Inventory of Psychosocial Functioning (IPF)34.5207 score on a scaleStandard Error 4.36232
PTSD Family Education (PFE)Inventory of Psychosocial Functioning (IPF)37.2820 score on a scaleStandard Error 4.10112
Primary

Inventory of Psychosocial Functioning (IPF)

The Inventory of Psychosocial Functioning (IPF) is an 80-item self-report measure designed to assess multiple dimensions of functional impairment related to psychiatric disturbances. Higher sum scores (range 0 to 100) indicate more functional impairment.

Time frame: Baseline

Population: Entire enrolled sample, Veteran partners only; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Inventory of Psychosocial Functioning (IPF)50.1419 score on a scaleStandard Error 3.53773
CBCT-Office Based (CBCT-OB)Inventory of Psychosocial Functioning (IPF)50.2336 score on a scaleStandard Error 3.63994
PTSD Family Education (PFE)Inventory of Psychosocial Functioning (IPF)47.5630 score on a scaleStandard Error 3.42855
Primary

Working Alliance Inventory- Short Form (WAI-S)

This adaptation of the Working Alliance Inventory- short form (WAI-S) includes 14 items assessing therapeutic alliance as reported by the patient on a 7-point Likert scale. Higher sum scores (14 to 98) represent higher patient-reported working alliance.

Time frame: Approximately week 3 of all treatment conditions

Population: Entire enrolled sample, both partners; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Working Alliance Inventory- Short Form (WAI-S)67.039390 score on a scaleStandard Error 1.3983512
CBCT-Office Based (CBCT-OB)Working Alliance Inventory- Short Form (WAI-S)71.116745 score on a scaleStandard Error 1.3928316
PTSD Family Education (PFE)Working Alliance Inventory- Short Form (WAI-S)68.748339 score on a scaleStandard Error 1.6357681
Primary

Working Alliance Inventory- Short Form (WAI-S)

This adaptation of the Working Alliance Inventory- short form (WAI-S) includes 14 items assessing therapeutic alliance as reported by the patient on a 7-point Likert scale. Higher sum scores (14 to 98) represent higher patient-reported working alliance.

Time frame: Approximately week 8 of all treatment conditions

Population: Entire enrolled sample, both partners; imputed using fully Bayesian model-consistent multiple imputation

ArmMeasureValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Working Alliance Inventory- Short Form (WAI-S)72.099053 score on a scaleStandard Error 1.3878994
CBCT-Office Based (CBCT-OB)Working Alliance Inventory- Short Form (WAI-S)73.882508 score on a scaleStandard Error 1.4738266
PTSD Family Education (PFE)Working Alliance Inventory- Short Form (WAI-S)75.647561 score on a scaleStandard Error 1.4537812
Secondary

Beck Depression Inventory-II (BDI-2)

The BDI is a 21-item self report questionnaire assessing symptoms of depression. Scores range from 0 to 63, with higher scores representing more severe symptoms.

Time frame: Mid Treatment (Approximately Week 5 of all treatment conditions)

Population: Entire enrolled sample, both partners, using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Beck Depression Inventory-II (BDI-2)Intimate Partners15.8047 score on a scaleStandard Error 2.19033
CBCT-Home Based (CBCT-HB)Beck Depression Inventory-II (BDI-2)Veterans19.9002 score on a scaleStandard Error 2.40992
CBCT-Office Based (CBCT-OB)Beck Depression Inventory-II (BDI-2)Intimate Partners12.4473 score on a scaleStandard Error 2.63256
CBCT-Office Based (CBCT-OB)Beck Depression Inventory-II (BDI-2)Veterans20.4560 score on a scaleStandard Error 2.2207
PTSD Family Education (PFE)Beck Depression Inventory-II (BDI-2)Intimate Partners13.2118 score on a scaleStandard Error 2.8279
PTSD Family Education (PFE)Beck Depression Inventory-II (BDI-2)Veterans23.4512 score on a scaleStandard Error 2.90633
Secondary

Beck Depression Inventory-II (BDI-2)

The BDI is a 21-item self report questionnaire assessing symptoms of depression. Scores range from 0 to 63, with higher scores representing more severe symptoms.

Time frame: 6-Months Post Treatment

Population: Entire enrolled sample, both partners; using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Beck Depression Inventory-II (BDI-2)Veterans18.0075 score on a scaleStandard Error 2.5142
CBCT-Home Based (CBCT-HB)Beck Depression Inventory-II (BDI-2)Intimate Partners12.1675 score on a scaleStandard Error 2.29771
CBCT-Office Based (CBCT-OB)Beck Depression Inventory-II (BDI-2)Intimate Partners11.5881 score on a scaleStandard Error 2.08941
CBCT-Office Based (CBCT-OB)Beck Depression Inventory-II (BDI-2)Veterans14.9098 score on a scaleStandard Error 2.42697
PTSD Family Education (PFE)Beck Depression Inventory-II (BDI-2)Veterans20.0467 score on a scaleStandard Error 2.57977
PTSD Family Education (PFE)Beck Depression Inventory-II (BDI-2)Intimate Partners11.1593 score on a scaleStandard Error 2.34132
Secondary

Beck Depression Inventory-II (BDI-2)

The BDI is a 21-item self report questionnaire assessing symptoms of depression. Scores range from 0 to 63, with higher scores representing more severe symptoms.

Time frame: 3- Months Post Treatment

Population: Entire enrolled sample, both partners; using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Beck Depression Inventory-II (BDI-2)Veterans19.7016 score on a scaleStandard Error 2.61738
CBCT-Home Based (CBCT-HB)Beck Depression Inventory-II (BDI-2)Intimate Partners11.8226 score on a scaleStandard Error 2.42731
CBCT-Office Based (CBCT-OB)Beck Depression Inventory-II (BDI-2)Veterans15.6977 score on a scaleStandard Error 2.59297
CBCT-Office Based (CBCT-OB)Beck Depression Inventory-II (BDI-2)Intimate Partners11.4500 score on a scaleStandard Error 2.28087
PTSD Family Education (PFE)Beck Depression Inventory-II (BDI-2)Veterans18.4080 score on a scaleStandard Error 2.63802
PTSD Family Education (PFE)Beck Depression Inventory-II (BDI-2)Intimate Partners12.1826 score on a scaleStandard Error 2.31299
Secondary

Beck Depression Inventory-II (BDI-2)

The BDI is a 21-item self report questionnaire assessing symptoms of depression. Scores range from 0 to 63, with higher scores representing more severe symptoms.

Time frame: 1 Month Post Treatment

Population: Entire enrolled sample, both partners, using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Beck Depression Inventory-II (BDI-2)Veterans18.6926 score on a scaleStandard Error 2.50075
CBCT-Home Based (CBCT-HB)Beck Depression Inventory-II (BDI-2)Intimate Partners12.5802 score on a scaleStandard Error 2.48624
CBCT-Office Based (CBCT-OB)Beck Depression Inventory-II (BDI-2)Veterans15.6840 score on a scaleStandard Error 2.42694
CBCT-Office Based (CBCT-OB)Beck Depression Inventory-II (BDI-2)Intimate Partners11.6098 score on a scaleStandard Error 2.09489
PTSD Family Education (PFE)Beck Depression Inventory-II (BDI-2)Veterans21.6229 score on a scaleStandard Error 2.59271
PTSD Family Education (PFE)Beck Depression Inventory-II (BDI-2)Intimate Partners11.5033 score on a scaleStandard Error 2.26777
Secondary

Beck Depression Inventory-II (BDI-2)

The BDI is a 21-item self report questionnaire assessing symptoms of depression. Scores range from 0 to 63, with higher scores representing more severe symptoms.

Time frame: Baseline

Population: Entire enrolled sample, both partners, using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Beck Depression Inventory-II (BDI-2)Veterans29.2906 score on a scaleStandard Error 2.01236
CBCT-Home Based (CBCT-HB)Beck Depression Inventory-II (BDI-2)Intimate Partners11.3114 score on a scaleStandard Error 1.32078
CBCT-Office Based (CBCT-OB)Beck Depression Inventory-II (BDI-2)Veterans26.6096 score on a scaleStandard Error 1.74223
CBCT-Office Based (CBCT-OB)Beck Depression Inventory-II (BDI-2)Intimate Partners11.8069 score on a scaleStandard Error 1.33799
PTSD Family Education (PFE)Beck Depression Inventory-II (BDI-2)Veterans26.7542 score on a scaleStandard Error 1.9177
PTSD Family Education (PFE)Beck Depression Inventory-II (BDI-2)Intimate Partners11.4000 score on a scaleStandard Error 1.48861
Secondary

Conflict Tactics Scale Short Form- (CTS-2S)

20-item self-report inventory yielding 5 scales. Most widely used measure of its kind. Scores on the Psychological Aggression and Negotiation subscales range from 0 to 24, with higher scores representing more Psychological Aggression and more Negotiation.

Time frame: 6-Months Post Treatment

Population: Entire enrolled sample, both partners; using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale4.2911 score on a scaleStandard Error 0.79419
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Psychological aggression subscale3.9574 score on a scaleStandard Error 0.6844
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale14.4958 score on a scaleStandard Error 1.06696
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale15.7043 score on a scaleStandard Error 0.97081
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale13.6076 score on a scaleStandard Error 1.13738
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale4.1617 score on a scaleStandard Error 0.7254
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale13.9513 score on a scaleStandard Error 1.15916
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Psychological aggression subscale4.5597 score on a scaleStandard Error 0.71441
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale15.0468 score on a scaleStandard Error 1.10333
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Psychological aggression subscale3.5832 score on a scaleStandard Error 0.67381
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale13.4718 score on a scaleStandard Error 1.06347
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale3.1872 score on a scaleStandard Error 0.65897
Secondary

Conflict Tactics Scale Short Form- (CTS-2S)

20-item self-report inventory yielding 5 scales. Most widely used measure of its kind. Scores on the Psychological Aggression and Negotiation subscales range from 0 to 24, with higher scores representing more Psychological Aggression and more Negotiation.

Time frame: Baseline

Population: Entire enrolled sample, both partners; using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale8.1739 score on a scaleStandard Error 0.58591
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Psychological aggression subscale8.9130 score on a scaleStandard Error 0.50296
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale17.5000 score on a scaleStandard Error 0.74129
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale18.4348 score on a scaleStandard Error 0.61042
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale17.7609 score on a scaleStandard Error 0.70689
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale8.5217 score on a scaleStandard Error 0.63149
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale18.2174 score on a scaleStandard Error 0.76828
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Psychological aggression subscale7.8696 score on a scaleStandard Error 0.60242
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale17.4889 score on a scaleStandard Error 0.86551
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Psychological aggression subscale7.5778 score on a scaleStandard Error 0.68423
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale18.7111 score on a scaleStandard Error 0.65568
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale7.8444 score on a scaleStandard Error 0.55592
Secondary

Conflict Tactics Scale Short Form- (CTS-2S)

20-item self-report inventory yielding 5 scales. Most widely used measure of its kind. Scores on the Psychological Aggression and Negotiation subscales range from 0 to 24, with higher scores representing more Psychological Aggression and more Negotiation.

Time frame: Mid Treatment (Approximately week 5 of all treatment conditions)

Population: Enrolled sample only, both partners; using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale4.3120 score on a scaleStandard Error 0.72809
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Psychological aggression subscale4.2366 score on a scaleStandard Error 0.72491
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale13.6238 score on a scaleStandard Error 1.02718
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale13.9197 score on a scaleStandard Error 1.01009
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale12.9316 score on a scaleStandard Error 0.95512
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale4.8690 score on a scaleStandard Error 0.64106
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale13.7363 score on a scaleStandard Error 0.89228
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Psychological aggression subscale4.6851 score on a scaleStandard Error 0.65959
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale14.2217 score on a scaleStandard Error 0.89814
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Psychological aggression subscale3.5465 score on a scaleStandard Error 0.65402
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale14.6018 score on a scaleStandard Error 0.9131
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale3.6182 score on a scaleStandard Error 0.70126
Secondary

Conflict Tactics Scale Short Form- (CTS-2S)

20-item self-report inventory yielding 5 scales. Most widely used measure of its kind. Scores on the Psychological Aggression and Negotiation subscales range from 0 to 24, with higher scores representing more Psychological Aggression and more Negotiation.

Time frame: 1 Month Post Treatment

Population: Entire enrolled sample, both partners; using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale4.1295 score on a scaleStandard Error 0.71564
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Psychological aggression subscale3.5965 score on a scaleStandard Error 0.65219
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale14.9523 score on a scaleStandard Error 0.9933
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale15.3302 score on a scaleStandard Error 0.90193
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale14.9261 score on a scaleStandard Error 1.03747
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale4.0524 score on a scaleStandard Error 0.6869
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale14.6470 score on a scaleStandard Error 0.99507
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Psychological aggression subscale4.7797 score on a scaleStandard Error 0.65758
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale14.3585 score on a scaleStandard Error 1.1189
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Psychological aggression subscale3.7661 score on a scaleStandard Error 0.68853
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale14.9224 score on a scaleStandard Error 0.94777
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale3.4079 score on a scaleStandard Error 0.63721
Secondary

Conflict Tactics Scale Short Form- (CTS-2S)

20-item self-report inventory yielding 5 scales. Most widely used measure of its kind. Scores on the Psychological Aggression and Negotiation subscales range from 0 to 24, with higher scores representing more Psychological Aggression and more Negotiation.

Time frame: 3- Months Post Treatment

Population: Entire enrolled sample, both partners; using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale14.7853 score on a scaleStandard Error 1.00807
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale15.0919 score on a scaleStandard Error 1.03404
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale4.0795 score on a scaleStandard Error 0.6941
CBCT-Home Based (CBCT-HB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate partners - Psychological aggression subscale3.7899 score on a scaleStandard Error 0.71769
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale14.8986 score on a scaleStandard Error 1.071
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale4.0335 score on a scaleStandard Error 0.69447
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale14.6806 score on a scaleStandard Error 1.04556
CBCT-Office Based (CBCT-OB)Conflict Tactics Scale Short Form- (CTS-2S)Intimate partners - Psychological aggression subscale4.5018 score on a scaleStandard Error 0.69773
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Psychological aggression subscale3.7106 score on a scaleStandard Error 0.60643
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Intimate partners - Psychological aggression subscale3.8952 score on a scaleStandard Error 0.66721
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Veterans - Negotiation subscale14.3893 score on a scaleStandard Error 1.1123
PTSD Family Education (PFE)Conflict Tactics Scale Short Form- (CTS-2S)Intimate Partners - Negotiation subscale14.3492 score on a scaleStandard Error 1.02322
Secondary

PTSD Checklist-5 (PCL-5)

The PCL-5 is a 20 item self report questionnaire assessing symptoms of PTSD based on DSM-V criteria. Scores range from 0 to 80, with higher scores representing more severe symptoms.

Time frame: Mid Treatment (Approximately week 5 of all treatment conditions)

Population: Entire enrolled sample, both partners, using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)PTSD Checklist-5 (PCL-5)Veterans38.0555 score on a scaleStandard Error 3.3583
CBCT-Home Based (CBCT-HB)PTSD Checklist-5 (PCL-5)Intimate Partners31.2492 score on a scaleStandard Error 4.04086
CBCT-Office Based (CBCT-OB)PTSD Checklist-5 (PCL-5)Veterans40.1717 score on a scaleStandard Error 3.38226
CBCT-Office Based (CBCT-OB)PTSD Checklist-5 (PCL-5)Intimate Partners25.7970 score on a scaleStandard Error 3.86422
PTSD Family Education (PFE)PTSD Checklist-5 (PCL-5)Veterans44.8501 score on a scaleStandard Error 3.61442
PTSD Family Education (PFE)PTSD Checklist-5 (PCL-5)Intimate Partners30.2030 score on a scaleStandard Error 3.93086
Secondary

PTSD Checklist-5 (PCL-5)

The PCL-5 is a 20 item self report questionnaire assessing symptoms of PTSD based on DSM-V criteria. Scores range from 0 to 80, with higher scores representing more severe symptoms.

Time frame: Baseline

Population: Entire enrolled sample, both partners, using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)PTSD Checklist-5 (PCL-5)Veterans50.3573 score on a scaleStandard Error 2.39404
CBCT-Home Based (CBCT-HB)PTSD Checklist-5 (PCL-5)Intimate Partners16.5869 score on a scaleStandard Error 2.09389
CBCT-Office Based (CBCT-OB)PTSD Checklist-5 (PCL-5)Veterans50.5211 score on a scaleStandard Error 2.2214
CBCT-Office Based (CBCT-OB)PTSD Checklist-5 (PCL-5)Intimate Partners16.6637 score on a scaleStandard Error 2.13649
PTSD Family Education (PFE)PTSD Checklist-5 (PCL-5)Veterans51.2357 score on a scaleStandard Error 2.20064
PTSD Family Education (PFE)PTSD Checklist-5 (PCL-5)Intimate Partners15.6440 score on a scaleStandard Error 1.94226
Secondary

PTSD Checklist-5 (PCL-5)

The PCL-5 is a 20 item self report questionnaire assessing symptoms of PTSD based on DSM-V criteria. Scores range from 0 to 80, with higher scores representing more severe symptoms.

Time frame: 6-Months Post Treatment

Population: Entire enrolled sample, both partners, using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)PTSD Checklist-5 (PCL-5)Veterans35.6725 score on a scaleStandard Error 3.70946
CBCT-Home Based (CBCT-HB)PTSD Checklist-5 (PCL-5)Partners27.8900 score on a scaleStandard Error 3.90941
CBCT-Office Based (CBCT-OB)PTSD Checklist-5 (PCL-5)Veterans31.0392 score on a scaleStandard Error 3.71211
CBCT-Office Based (CBCT-OB)PTSD Checklist-5 (PCL-5)Partners25.1507 score on a scaleStandard Error 3.9443
PTSD Family Education (PFE)PTSD Checklist-5 (PCL-5)Veterans39.8824 score on a scaleStandard Error 3.63766
PTSD Family Education (PFE)PTSD Checklist-5 (PCL-5)Partners27.9336 score on a scaleStandard Error 3.78858
Secondary

PTSD Checklist-5 (PCL-5)

The PCL-5 is a 20 item self report questionnaire assessing symptoms of PTSD based on DSM-V criteria. Scores range from 0 to 80, with higher scores representing more severe symptoms.

Time frame: 3- Months Post Treatment

Population: Entire enrolled sample, both partners, using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)PTSD Checklist-5 (PCL-5)Veterans36.2751 score on a scaleStandard Error 3.66118
CBCT-Home Based (CBCT-HB)PTSD Checklist-5 (PCL-5)Intimate Partners27.5520 score on a scaleStandard Error 4.20814
CBCT-Office Based (CBCT-OB)PTSD Checklist-5 (PCL-5)Veterans30.1964 score on a scaleStandard Error 3.83395
CBCT-Office Based (CBCT-OB)PTSD Checklist-5 (PCL-5)Intimate Partners26.1153 score on a scaleStandard Error 3.98684
PTSD Family Education (PFE)PTSD Checklist-5 (PCL-5)Veterans38.3393 score on a scaleStandard Error 3.43143
PTSD Family Education (PFE)PTSD Checklist-5 (PCL-5)Intimate Partners28.9425 score on a scaleStandard Error 4.09243
Secondary

PTSD Checklist-5 (PCL-5)

The PCL-5 is a 20 item self report questionnaire assessing symptoms of PTSD based on DSM-V criteria. Scores range from 0 to 80, with higher scores representing more severe symptoms.

Time frame: 1 Month Post Treatment

Population: Entire enrolled sample, both partners, using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)PTSD Checklist-5 (PCL-5)Veterans34.1452 score on a scaleStandard Error 3.75753
CBCT-Home Based (CBCT-HB)PTSD Checklist-5 (PCL-5)Intimate partners28.9042 score on a scaleStandard Error 3.92662
CBCT-Office Based (CBCT-OB)PTSD Checklist-5 (PCL-5)Veterans31.1537 score on a scaleStandard Error 3.3948
CBCT-Office Based (CBCT-OB)PTSD Checklist-5 (PCL-5)Intimate partners25.2462 score on a scaleStandard Error 3.54497
PTSD Family Education (PFE)PTSD Checklist-5 (PCL-5)Veterans42.1752 score on a scaleStandard Error 3.53403
PTSD Family Education (PFE)PTSD Checklist-5 (PCL-5)Intimate partners27.4718 score on a scaleStandard Error 3.14068
Secondary

State-Trait Anger Inventory (STAXI)

The STAXI-2 is a self-report questionnaire assessing state and trait anger. The State subscale (15 items) ranges from 15 to 60, and the Trait subscale (10 items) ranges from 10 to 40, with higher scores representing more anger.

Time frame: Baseline

Population: Entire enrolled sample, both partners; using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Intimate Partners - Trait subscale15.9926 score on a scaleStandard Error 0.57623
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Intimate Partners - State subscale16.5972 score on a scaleStandard Error 0.48672
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale22.7246 score on a scaleStandard Error 0.85906
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Veterans - State subscale21.9205 score on a scaleStandard Error 1.44069
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale22.4783 score on a scaleStandard Error 0.76595
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Intimate Partners - State subscale16.5322 score on a scaleStandard Error 0.58332
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Intimate Partners - Trait subscale17.3426 score on a scaleStandard Error 0.8747
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Veterans - State subscale23.3263 score on a scaleStandard Error 1.66076
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Veterans - State subscale23.6691 score on a scaleStandard Error 1.6697
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Intimate Partners - State subscale16.3185 score on a scaleStandard Error 0.46291
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Intimate Partners - Trait subscale16.2507 score on a scaleStandard Error 0.76938
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale23.6012 score on a scaleStandard Error 1.08541
Secondary

State-Trait Anger Inventory (STAXI)

The STAXI-2 is a self-report questionnaire assessing state and trait anger. The State subscale (15 items) ranges from 15 to 60, and the Trait subscale (10 items) ranges from 10 to 40, with higher scores representing more anger.

Time frame: Mid Treatment (Approximately week 5 of all treatment conditions)

Population: Entire enrolled sample, both partners; using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Veterans - State subscale20.8798 score on a scaleStandard Error 1.3931
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Intimate Partners - State subscale19.0822 score on a scaleStandard Error 1.19655
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale19.5022 score on a scaleStandard Error 1.03512
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Intimate Partners - Trait subscale17.0778 score on a scaleStandard Error 1.00838
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Intimate Partners - Trait subscale17.0418 score on a scaleStandard Error 0.96957
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Veterans - State subscale20.5599 score on a scaleStandard Error 1.49279
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale20.3355 score on a scaleStandard Error 1.04492
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Intimate Partners - State subscale17.2434 score on a scaleStandard Error 1.09043
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Intimate Partners - Trait subscale16.8182 score on a scaleStandard Error 1.02438
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Intimate Partners - State subscale17.7080 score on a scaleStandard Error 1.27415
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale21.6513 score on a scaleStandard Error 1.32337
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Veterans - State subscale23.5422 score on a scaleStandard Error 1.99174
Secondary

State-Trait Anger Inventory (STAXI)

The STAXI-2 is a self-report questionnaire assessing state and trait anger. The State subscale (15 items) ranges from 15 to 60, and the Trait subscale (10 items) ranges from 10 to 40, with higher scores representing more anger.

Time frame: 1 Month Post Treatment

Population: Entire enrolled sample, both partners; using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Veterans - State subscale19.6216 score on a scaleStandard Error 1.51017
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale19.2848 score on a scaleStandard Error 1.12873
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Intimate Partners - Trait subscale16.4488 score on a scaleStandard Error 1.1342
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Intimate Partners - State subscale17.7897 score on a scaleStandard Error 1.25246
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Intimate Partners - Trait subscale16.6423 score on a scaleStandard Error 1.12928
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Veterans - State subscale18.6260 score on a scaleStandard Error 1.36216
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Intimate Partners - State subscale17.8016 score on a scaleStandard Error 1.2199
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale19.0268 score on a scaleStandard Error 1.11595
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Intimate Partners - State subscale17.9761 score on a scaleStandard Error 1.24466
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale21.5299 score on a scaleStandard Error 1.35408
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Veterans - State subscale22.0156 score on a scaleStandard Error 1.57502
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Intimate Partners - Trait subscale16.4590 score on a scaleStandard Error 1.0105
Secondary

State-Trait Anger Inventory (STAXI)

The STAXI-2 is a self-report questionnaire assessing state and trait anger. The State subscale (15 items) ranges from 15 to 60, and the Trait subscale (10 items) ranges from 10 to 40, with higher scores representing more anger.

Time frame: 3- Months Post Treatment

Population: Entire enrolled sample, both partners; using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale18.7056 score on a scaleStandard Error 1.20307
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Intimate partners - Trait subscale15.9029 score on a scaleStandard Error 1.22085
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Veterans - State subscale20.5553 score on a scaleStandard Error 1.69937
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Intimate partners - State subscale17.8972 score on a scaleStandard Error 1.23307
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Intimate partners - State subscale17.4860 score on a scaleStandard Error 1.23456
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale18.9492 score on a scaleStandard Error 1.32233
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Veterans - State subscale19.7572 score on a scaleStandard Error 1.76798
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Intimate partners - Trait subscale16.9785 score on a scaleStandard Error 1.08067
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Intimate partners - State subscale18.8452 score on a scaleStandard Error 1.25349
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Intimate partners - Trait subscale16.7127 score on a scaleStandard Error 1.14092
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Veterans - State subscale20.0755 score on a scaleStandard Error 1.48921
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale20.5660 score on a scaleStandard Error 1.37056
Secondary

State-Trait Anger Inventory (STAXI)

The STAXI-2 is a self-report questionnaire assessing state and trait anger. The State subscale (15 items) ranges from 15 to 60, and the Trait subscale (10 items) ranges from 10 to 40, with higher scores representing more anger.

Time frame: 6-Months Post Treatment

Population: Entire enrolled sample, both partners; using multiply imputed data

ArmMeasureGroupValue (MEAN)Dispersion
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Veterans - State subscale19.9870 score on a scaleStandard Error 1.37717
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Intimate Partners - State subscale17.5131 score on a scaleStandard Error 1.26957
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Intimate Partners - Trait subscale16.0526 score on a scaleStandard Error 1.22372
CBCT-Home Based (CBCT-HB)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale18.4906 score on a scaleStandard Error 1.07693
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Intimate Partners - State subscale17.2149 score on a scaleStandard Error 1.19453
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale18.9074 score on a scaleStandard Error 1.25158
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Veterans - State subscale20.0932 score on a scaleStandard Error 1.67819
CBCT-Office Based (CBCT-OB)State-Trait Anger Inventory (STAXI)Intimate Partners - Trait subscale16.2891 score on a scaleStandard Error 1.0904
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Intimate Partners - Trait subscale16.0928 score on a scaleStandard Error 1.0977
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Intimate Partners - State subscale17.7645 score on a scaleStandard Error 1.1888
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Veterans - State subscale20.8182 score on a scaleStandard Error 1.31146
PTSD Family Education (PFE)State-Trait Anger Inventory (STAXI)Veterans - Trait subscale19.7710 score on a scaleStandard Error 1.14792

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026