Cognitive Function, Energy, Food Cravings, Mood
Conditions
Keywords
Micro bouts, Physical Activity
Brief summary
This study is designed to test the effects of six 5 minute microbursts of physical activity spread across the day as compared to either a sedentary control condition or a single 30 minute bout of moderate intensity physical activity on cognitive function, self-reported energy levels, aspects of eating behavior and measures of metabolic health. The primary hypotheses are: 1. Hourly 5 minute bouts of moderate intensity exercise during the day will increase afternoon cognitive function as compared to a no exercise condition. 2. Hourly 5 minute bouts of moderate intensity exercise during the day will increase afternoon cognitive function more than a single 30 minute AM bout. Secondary exploratory hypotheses include 1. Hourly 5 minute bouts of moderate intensity exercise during the day will increase self-reported energy levels, reduce orexigenic appetitive measures and improve measures of metabolic health as compared to a no exercise condition. 2. Hourly 5 minute bouts of moderate intensity exercise during the day will increase self-reported energy levels, reduce orexigenic appetitive measures and improve measures of metabolic health more than a single 30 minute AM bout.
Interventions
BEHAVIORALphysical activity
Sponsors
University of Colorado, Denver
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
19 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
1. All ethnic groups and both genders 2. Age: Lower age limit: 19 years; Upper age limit: 45 years 3. Body-mass Index: Lower BMI limit: 18.5 kg/m2; Upper BMI limit: 29.9 kg/m2 4. Willing to adhere to caffeine restrictions of no more than two 16 ounce beverages in the morning of each study day with no caffeine intake after 12:00pm on any of the three study days
Exclusion criteria
1. History of cardiovascular disease, including coronary artery disease, congestive heart failure, & unstable angina, or uncontrolled hypertension (\>140/90 mm Hg) 2. Currently smoking or stopped smoking in the last 6 months 3. Medications affecting weight, energy intake, or energy expenditure in the last 6 months 4. Use of oral steroids 5. History of stroke or seizures, thyroid disease, type 1 or 2 diabetes, Cushing's syndrome, cerebrovascular, renal disease, hepatic disease, arrhythmias 6. Cancer requiring treatment in the past 5 years, with the exception of skin cancers other than melanoma 7. Infectious diseases: Self-reported HIV positivity or active tuberculosis 8. Inability to exercise for more than 30 minutes on a treadmill at moderate intensity 9. Currently pregnant, lactating or less than 6 months post-partum 10. History of a major psychiatric disorder including schizophrenia, bipolar illness or psychotic depression 11. Score of \>25 on Beck Depression Inventory 12. No recreational drug use including marijuana in the past 1 year
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Energy and Mood level | During each of the three separate study days energy and mood levels are assessed at (in minutes): T0, T40, T70, T80, T90, T120, T140, T230, T350, T390, T400, T405, T410, and T435 | Self-perceived energy and mood were measured by using visual analogue scales (VAS) as described below at baseline. |
| Change in Cognitive function | During each of the three separate study days cognitive function is measured at (in minutes): T410 | The flanker task is used to measure cognitive function |
| Change in Cognitive Function | During each of the three separate study days cognitive function is measured at (in minutes): T425 | After the Flanker task, the Comprehensive Trail Making Test is used to measure cognitive function during each study day. |
Outcome results
None listed