Retinal Blood Vessels, Age-Related Macular Degeneration
Conditions
Brief summary
Retinal blood flow measurement is of scientific and clinical value. For this purpose retinal vessel morphology (such as diameter, vessel wall thickness, etc) determination is crucial. Different imaging modalities might provide divergent results. Thus, quantification of such differences is valuable. The present study aims to reveal and quantify differences in vessel morphology between fundus photography, fundus angiography, and optical coherence tomography in health and disease.
Detailed description
This is considered a pilot study and will pe performed on patients scheduled for routine fluorescein angiography. During the study day the following procedures will be performed: * Medical history and concomitant medication * Blood pressure and heart rate * Assessment of visual acuity using Snellen vision charts * Biomicroscopy * Intraocular pressure * Funduscopy * IOL-Master axial length measurement * Fundusphotography * Optical coherence tomography * Fluorescein Angiography Fundus photography analysis will be performed with an automated software and analysis of both angiography and optical coherence tomography will be performed via the devices inbuilt software.
Interventions
Sections including the retinal vasculature will be taken.
Video fluorescein angiography from one eye of each subject will be performed
30 and 50 degree fundus images
Sponsors
Study design
Eligibility
Inclusion criteria
* written informed consent, clear media
Exclusion criteria
* any abnormality preventing reliable vessel measurement, pregnancy,
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| retinal vessel diameter | 5 minutes |
Secondary
| Measure | Time frame |
|---|---|
| retinal vessel reflectivity | 5 minutes |
Countries
Austria