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Multimodal Imaging of Retinal Vessels

Retinal Vessel Morphology in Multimodal Imaging

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02717026
Acronym
MIR
Enrollment
50
Registered
2016-03-23
Start date
2015-07-31
Completion date
2018-01-31
Last updated
2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retinal Blood Vessels, Age-Related Macular Degeneration

Brief summary

Retinal blood flow measurement is of scientific and clinical value. For this purpose retinal vessel morphology (such as diameter, vessel wall thickness, etc) determination is crucial. Different imaging modalities might provide divergent results. Thus, quantification of such differences is valuable. The present study aims to reveal and quantify differences in vessel morphology between fundus photography, fundus angiography, and optical coherence tomography in health and disease.

Detailed description

This is considered a pilot study and will pe performed on patients scheduled for routine fluorescein angiography. During the study day the following procedures will be performed: * Medical history and concomitant medication * Blood pressure and heart rate * Assessment of visual acuity using Snellen vision charts * Biomicroscopy * Intraocular pressure * Funduscopy * IOL-Master axial length measurement * Fundusphotography * Optical coherence tomography * Fluorescein Angiography Fundus photography analysis will be performed with an automated software and analysis of both angiography and optical coherence tomography will be performed via the devices inbuilt software.

Interventions

DEVICEOptical coherence tomography

Sections including the retinal vasculature will be taken.

Video fluorescein angiography from one eye of each subject will be performed

30 and 50 degree fundus images

Sponsors

Medical University of Graz
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* written informed consent, clear media

Exclusion criteria

* any abnormality preventing reliable vessel measurement, pregnancy,

Design outcomes

Primary

MeasureTime frame
retinal vessel diameter5 minutes

Secondary

MeasureTime frame
retinal vessel reflectivity5 minutes

Countries

Austria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026