Clinical Study of Injectable Ceramics Bone Graft Substitute Containing rhBMP-2

Clinical Study to Evaluate Efficacy and Safety of Inject BMP(Beta-TCP Containing rhBMP-2) for Socket Preservation After Extraction of a Single-rooted Tooth: A Randomized, Outcomes Assessor-Blinded, Multi-center, Prospective Trial.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02714829

Acronym

rhBMP-2

Enrollment

Registered

2016-03-22

Start date

2016-04-30

Completion date

2018-04-30

Last updated

2018-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alveolar Bone Preservation, Bone Graft

Keywords

Injectable Ceramics Bone Graft Substitute Containing rhBMP-2

Brief summary

This is a prospective, outcomes assessor-blinded, randomized study to evaluate the efficacy and safety of Inject BMP(Injectable Ceramics Bone Graft Substitute Containing rhBMP-2) for socket preservation after extraction of a single-rooted tooth, compared to ExcelOS-inject(Injectable Ceramics Bone Graft Substitute).

Detailed description

Inject BMP is Injectable Ceramics Bone Graft Substitute(ExcelOS-inject) containing rhBMP-2. Recombinant human Bone morphogenetic protein 2 (rhBMP-2) stimulates the production of bone.

Interventions

DEVICEInject BMP

Injection of ExcelOS-inject(beta-TCP) containing rhBMP-2.

DEVICEExcelOS-inject

Injection of ExcelOS-inject(beta-TCP) without rhBMP-2.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

19 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Persons without periodontal disease

Exclusion criteria

* Women who are pregnant or plan to be pregnant within study period

Design outcomes

Primary

Measure	Time frame
compared the changed height and standard height by computed tomography.	at 12 weeks after surgery

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 20, 2026