Oral Hyoscine Butyl Bromide Versus Diclofenac Potassium Before Office Hysteroscopy

Randomized Clinical Trial of Oral Hyoscine Butyl Bromide Versus Diclofenac Potassium in Reducing Pain During Office Hysteroscopy

Status

Completed

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02714699

Enrollment

129

Registered

2016-03-21

Start date

2016-10-31

Completion date

2017-05-31

Last updated

2018-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endoscopy

Brief summary

The study aims to determine the efficacy of oral hyoscine butyl bromide versus diclofenac potassium on the pain scores during office hysteroscopy

Interventions

DRUGdiclofenac potassium

patients will take oral diclofenac potassium; two tablets (cataflam 25 mg) and one tablet placebo one hour before the procedure

DRUGhyoscine butyl bromide

patients will take oral hyoscine-N- butyl bromide; 2 tablets (buscopan 10 mg) one hour before the procedure

DRUGplacebo

patients will take oral placebo; 2 tablets one hour before the procedure

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Patients that must perform a diagnostic hysteroscopy. 2. Acceptance to participate in the study. 3. Signed informed consent. 4. Not taking analgesics (acetaminophen, ibuprofen, mefenamic acid) before admission. 5. Absence of sedative use before admission

Exclusion criteria

1. Hypersensitivity to drugs 2. refusal of the patient 3. Patients are pregnant.

Design outcomes

Primary

Measure	Time frame
Mean pain score during hysteroscopy	intraoperative

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026