Povidone-iodine Versus Saline in Vaginal Cleansing Before Office Hysteroscopy

A Comparison Between Povidone-iodine and Normal Saline in Vaginal Cleansing Before Office Hysterosocpy: a Randomized Controlled Trial

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02713074

Acronym

PISOH

Enrollment

147

Registered

2016-03-18

Start date

2016-10-31

Completion date

2017-07-31

Last updated

2017-07-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Infection

Brief summary

The normal saline is used in medicine as an intravenous isotonic infusion and for cleaning wounds. It is a mild but effective cleaning agent and will not harm normal tissue, unlike many stronger antiseptics. It is available and inexpensive in comparison to povidone iodine.

Interventions

DRUGpovidone-iodine

The patients will be subjected to povidone-iodine (Betadine7.5%) for vaginal cleaning before office hysteroscopy

DRUGnormal saline

The patients will be subjected to normal saline (Sod. Chloride 0.9%, Nile) for vaginal cleaning

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

1 - All women who will subject to office Hysterosocpy for gynecological problems

Exclusion criteria

1. All patients have current vaginitis or urinary tract infection before the hysteroscopy 2. Diabetic women. 3. Women with body mass index \> 25 kg/m2.

Design outcomes

Primary

Measure	Time frame
rate of postoperative vaginal irritation symptoms	24 hours

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026