Gingival Recession
Conditions
Brief summary
Backgroung: Various agents are used to reduce post-operative complications associated with palatal donor site surgery for free gingival graft (FGG) harvesting. This study was conducted to evaluate the effects of platelet-rich fibrin (PRF) on palatal wound healing.
Detailed description
125 patients with isolated recessions were treated. The connective tissue graft was obtained by the de-epithelialization of a free gingival graft in both groups. Three different hemostatic treatments were randomized; PRF with cyanoacrilate adhesive (PRF group, n:42), cyanoacrilate adhesive alone (BC group, n:42) and sterile wet gauze compression (WG group, n:41). Immediate and delayed bleeding, pain, epithelialization, feeding habits and sensation scores were recorded for different time points.
Interventions
OTHERPlatelet Rich Fibrin
Immediate and delayed bleeding, pain, epithelialization, feeding habits and sensation scores were recorded after PRF placing on palatal wounds.
OTHERButyl cyanoacrylate
Immediate and delayed bleeding, pain, epithelialization, feeding habits and sensation scores were recorded after Butyl Cyanoacrylate application on palatal wounds.
OTHERWet gauze
Immediate and delayed bleeding, pain, epithelialization, feeding habits and sensation scores were recorded after wet gauze pressure on palatal wounds.
Sponsors
Cukurova University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
21 Years to 48 Years
Healthy volunteers
Yes
Inclusion criteria
* no contraindications for periodontal surgery; * full-mouth plaque score of \<10% * full-mouth bleeding score of \<15%.
Exclusion criteria
* previously undergone surgery for a graft harvested from the palate * presence of systemic disease or taking medication known to interfere with periodontal health * smokers * possible coagulation disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Epithelialization | One month | Assessed according to the toluedine blue coloring |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Immediate Bleeding | 1 hour | Bleeding assesment for post-operative one hour |
| Pain | 3 months | Visual Analague Scale scores |
| Sensibility disorders | One month | visual analogue scale scores |
| feeding habits | One month | visual analogue scale scores |
| Delayed bleeding | 1 week | Bleeding assesment for post-operative one week |
Outcome results
None listed