Indomethacin Use in Pain Relief During Intrauterine Device Insertion

Rectal Indomethacin Use in Pain Relief During Intrauterine Device Insertion: A Randomized Controlled Trial

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02711358

Acronym

INDO-IUD

Enrollment

120

Registered

2016-03-17

Start date

2016-03-31

Completion date

2016-10-31

Last updated

2016-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Family Planning

Brief summary

The aim of the investigators study is to test the analgesic effect of rectal indomethacin during Intrauterine device insertion.

Interventions

DRUGindomethacin suppositories

The patients will be instructed to self-administer a single rectal dose of 50 mg indomethacin 30 min before the scheduled time of the procedure

DRUGplacebo

The patient swill be instructed to self-administer a single rectal dose of placebo 30 min before the scheduled time of the procedure

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 49 Years

Healthy volunteers

Inclusion criteria

* Women not taken analgesics or anxiolytics in the 24 hours prior insertion * Women not taken misoprostol prior to intrauterine device insertion * Women who will accept to participate in the study

Exclusion criteria

* Any contraindication to intrauterine device placement

Design outcomes

Primary

Measure	Time frame
Mean pain score during IUD insertion	intraoperative

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026