Optimal Analgesia in Acute Gastroenteritis

Optimal Analgesia in Acute Gastroenteritis in Emergency Department Setting: Dipyrone Versus Papaverine

Status

Terminated

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02711241

Enrollment

Registered

2016-03-17

Start date

2010-06-30

Completion date

2010-12-31

Last updated

2016-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroenteritis

Keywords

Gastroenteritis, Analgesia, Emergency department

Brief summary

The purpose of this study is to find out an optimal way of analgesia in case of acute infectious gastroenteritis the investigators are going to compare two medicines that are used on everyday basis (without being ever before subject to scientifical study): Dipyrone and papaverine The study is done in the Emergency Department setting. Thus, only first 6 hours of treatment is included in study

Interventions

DRUGDipyrone

1 gram by slow IV infusion

DRUGPapaverine

80 mg by slow intravenous infusion

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* acute gastroenteritis * VAS scale of pain perception at least 4

Exclusion criteria

* pregnancy * allergy to any one of study preparations * blood pressure less than 85 on admission * surgical condition (acute abdomen) suspected or diagnosed

Design outcomes

Primary

Measure	Time frame
Change in pain assessment (VAS) as opposed the pain assessment on admission	30 min, 1 hour, 2 hours, on discharge (up to 24 hours)

Secondary

Measure	Time frame
Need for second analgesic medicine	24 hours

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026