Severe Obesity
Conditions
Brief summary
To evaluate effect on comorbid disease and weight loss in the long-term (\>five years) after Roux-en-Y gastric bypass (RYGB) surgery for severe obesity.
Detailed description
Individuals with severe obesity frequently have comorbid diseases, e.g. diabetes, hypertension, hyperlipidemia, and sleep apnea. We will study the remission rate and weight loss in the long-term (10 years) after Roux-en-Y gastric bypass (RYGB) surgery in a nationwide large group of patients.
Interventions
PROCEDUREGastric bypass
Gastric bypass surgery, i.e., small gastric pouch and excluded main stomach
Sponsors
Karolinska Institutet
The Scandinavian Obesity Surgery Registry
Uppsala University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Registered individuals in Scandinavian Obesity Surgery Registry (SOReg) having had gastric bypass
Exclusion criteria
* All other operations
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in comorbid conditions, as defined by use of pharmacological treatment | 10 years | Remission of diabetes mellitus, hypertension, dyslipidemia, and depression as defined by use of pharmacological treatment, and sleep apnea as defined by use of CPAP. Data will be collected from SOReg. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients with pathological laboratory data (corresponding to the studied comorbid conditions) | 10 years | Glucose, HbA1c, LDL, HDL, triglycerides, and blood pressure |
| Weight loss | 10 years | Peroperative weight (in kg) minus current weight (in kg) |
| BMI loss | 10 years | Peroperative BMI minus current BMI. Weight and height will be combined to report BMI in kg/m\^2. |
Countries
Sweden
Contacts
Primary ContactErik Näslund
Backup ContactMagnus Sundbom
Outcome results
None listed