Pain Relief With HSG
Conditions
Brief summary
Many oral analgesic drugs such as nonsteroidal anti-inflammatory drug(NSAID) are used to relieve pain from gynecological procedure and dysmenorrhea. Hyoscine-N-butyl bromide, an antispasmodic drug are commonly used for relief of smooth muscle spasms and can use to relieve genito-urinary spasm. Some studies reported hyoscine can't relieve pain in minor gynecological procedures. So the efficacy of hyoscine use are still controversial and no previous studies investigated its efficacy for pain relief in HSG procedure.
Interventions
oral hyoscine butyl bromide; 2 tablets (buscopan 10 mg) 30 minutes before the procedure
DRUGplacebo
oral placebo; 2 tablets 30 minutes before the procedure
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 42 Years
Healthy volunteers
No
Inclusion criteria
The infertile women who indicated for HSG.
Exclusion criteria
* contraindications to Hyoscine or NSAID - known sensitivity to these drugs * known sensitivity to contrast media * abnormal uterine bleeding * genital tract infection * suspected pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean pain score during. hysterosalpingography by visual analog scale | intraoperative |
Secondary
| Measure | Time frame |
|---|---|
| Mean pain score after hysterosalpingography | 30 minutes |
Countries
Egypt
Outcome results
None listed