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Lateral Occlusion of Uterine Artery in Total Laparoscopic Hysterectomy

Lateral Versus Cervical Coagulation of the Uterine Artery in Benign Hysterectomy: A Randomized Controlled Study

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02709460
Enrollment
60
Registered
2016-03-16
Start date
2016-01-31
Completion date
2019-12-01
Last updated
2019-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Hemorrhage

Keywords

hematoma, complication, hysterectomy

Brief summary

Laparoscopic hysterectomy is associated with complications in form of infections and subsequently dehiscence of the vault. This is a serious complication. The infection may be related to the frequently observed postoperative hematoma following traditional laparoscopic hysterectomy where the uterine artery is coagulated and divided at the cervical entry into the uterus. By coagulation of the uterine artery laterally close to the internal iliac artery this problem may be eliminated due to the much less bleeding observed during this procedure.

Detailed description

Laparoscopic hysterectomy (removal of the uterus) is today a well-described method for the removal of the uterus. The operation is offered in case of bleeding disorders where other treatments have been unsuccessful, uterine fibroids or other conditions requiring surgery with removal of the uterus. The operation is done today in most cases by dividing the uterine artery at the entrance to the cervix, where the artery divides into one ascending and descending branch. The most common complication of hysterectomy is bleeding perioperative well as postoperatively, which may result in a hematoma above the vaginal vault. Through the years different methods have been tried to reduce this complication, including tranexamic acid without great success. The hematoma may result in infection postoperative and subsequent poor healing, with the possibility of dehiscence of the vault. In the worst case, the gut is displaced through the vagina postoperatively. This condition can lead to diffuse peritonitis, which can be fatal in rare cases. Since the hemostasis related to the dividing of the artery uterine can be problematic, especially in case of fibroids it may be a technical advantage to coagulate the Uterine artery at the exit of the Internal Iliac artery. This operation also ensures identification of the ureter, which can be spared. Lesions to the ureter are detected in up to 1% of all surgical procedures at hysterectomy. Dividing of the Uterine artery at the Internal Iliac Artery also ensures that the artery can be divided with minimal bleeding at the cervix.

Interventions

PROCEDURELateral occlusion

Lateral occlusion close to the internal Iliac artery

Cervical occlusion of the uterine artery

Sponsors

Odense University Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Women submitted to total laparoscopic hysterectomy

Exclusion criteria

* Women \<18 years * Women no able to understand the study or not native in Danish * Women with uterine malignancy * Women with suspicion of pelvic mass * Women with abnormal coagulation * Women receiving glucocorticoid treatment * Women receiving anticoagulant treatment or have not followed prescription in relation to surgery

Design outcomes

Primary

MeasureTime frame
Frequency of postoperative hematoma2 years

Countries

Denmark

Contacts

Primary ContactVibeke Lysdal, Consultant
mr@rsyd.dk+4560113333

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026