Surgery
Conditions
Brief summary
Arterial pulse pressure variation induced by mechanical ventilation (ΔPP) is considered one of the best parameter to predict fluid responsiveness in patients under general anaesthesia. Pleth Variability Index (PVI) has been proposed as a less invasive alternative. However, the pneumoperitoneum has been recently seen suggested as a limitation to their interpretation. The aim of this observational study is to compare changes in ΔPP and PVI related to autotransfusion associated with a Trendelenburg manoeuver before and during laparoscopy in patients undergoing elective surgery.
Interventions
DEVICEPVI and deltaPP after trendelenburg position change
Comparison of hemodynamic parameters during surgery after position change
Sponsors
Brugmann University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiologists (ASA) score I-II * scheduled for elective abdominal laparoscopic surgery * with written informed consent * more than 18 years * Body Mass Index \< 40 kg.m-2 * no supraventricular arrhythmias * no heart failure with ejection fraction \<25 % * no peripheral vascular * no severe respiratory disease * no end stage renal failure (creatinine clearance \<30ml/min).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pleth variability index (in %) | 5 minutes | Before/after trendelenburg positioning in laparoscopic surgery |
| Pulse Pressure variation (deltaPP) (in %) | 5 minutes | Before/after trendelenburg positioning in laparoscopic surgery |
Countries
Belgium
Outcome results
None listed