Standardization of a Novel Self-administered Tablet Computer-based Clinical Screening Tool for Adverse Postoperative Cognitive Outcomes

Standardization of a Novel Self-administered Tablet Computer-based Clinical Screening Tool for Adverse Postoperative Cognitive Outcomes: A Neuropsychological Study in Non-surgical Volunteers

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02708823

Acronym

CogCheck-Norm

Enrollment

334

Registered

2016-03-15

Start date

2016-12-31

Completion date

2017-04-30

Last updated

2018-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delirium

Keywords

Postoperative delirium, Risk assessment, Clinical screening tool, Tablet computer

Brief summary

Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are common complications after surgery and may affect elderly patients in particular. CogCheck, an application for tablet computers, was developed with the intention to assist preoperative risk screening for POD and POCD in surgical patients. The aim of this study is to generate normative data with cognitively healthy participants for the application.

Detailed description

Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are common complications after surgery and may affect elderly patients in particular. Prior studies found risk factors for POD and POCD which are present preoperatively, e.g. older age and pre-existing cognitive impairment. However, the preoperative risk of postoperative adverse cognitive outcomes (POD and POCD) is often not screened in routine clinical practice as it is time-consuming and requires trained personnel. In 2014, the application for tablet computers Delirium Risk Profile (DRP) was developed at the University Hospital Basel to assist preoperative screening in surgical patients. The application was later renamed CogCheck as the scope of the tool was extended to POD and POCD risk assessment. The aim of this study is to provide normative data for the application. Ultimately, the objective is to assist health care providers in the evaluation of patients' cognitive functions by routinely using the application in preoperative clinics.

Interventions

OTHERCogCheck application

The application is administered once to all study participants.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Age ≥ 65 years * Education ≥ 7 years * Fluency in the German language * Written informed consent

Exclusion criteria

* History of cognitive impairment * Signs of depression * Severe sensory or motor impairment interfering with cognitive testing * Serious somatic disease, disease or event affecting the central nervous system (head trauma with loss of consciousness \> 5 minutes, any brain surgery, general anesthesia within the last 3 months, alcoholism, intoxication with neurotoxic substances) * Cerebrovascular disease * Regular medication with psychoactive drugs except for benzodiazepines * Participation in any cognitive study within the last 3 months or previous participation in a study using the application.

Design outcomes

Primary

Measure	Time frame	Description
CogCheck	Baseline.	Score in a self-administered tablet computer-based neuropsychological assessment.

Secondary

Measure	Time frame	Description
Mini-Mental State Examination (MMSE)	Baseline.	Obtained score in MMSE.
Geriatric Depression Scale (GDS)	Baseline.	Obtained score in GDS.
Consortium to Establish a Registry for Alzheimer's Disease - Neuropsychological Assessment Battery (CERAD-NAB)	Baseline.	Obtained score in CERAD-NAB.

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026