Development of a MID for the 1-minute Sit-to-stand Test

Development of a Minimal Important Difference for the 1-minute Sit-to-stand Test

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02708719

Enrollment

105

Registered

2016-03-15

Start date

2016-04-30

Completion date

2017-12-31

Last updated

2018-02-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD

Keywords

COPD, MID, 1-minute sit-to-stand-test

Brief summary

The purpose of this study is to determine the minimal important difference (MID) for the 1-minute-sit-to-stand-test (STST) with an anchor-based method.

Detailed description

In this study we develop the minimal important difference for the 1-minute sit-to-stand-test (STST) with an anchor-based method. First step of this study is to find out the differences in the number of repetitions during 1-minute STST, 6-minute walk distance and health-related quality of life from pre to post inpatient pulmonary Rehabilitation program (3 weeks Duration) in the Schoen-Klinik Berchtesgadener Land. In Addition, Balance tests on the Leonardo-Mechanograph will be performed and the Hospital Anxiety and Depression Scale (HADS) and Chronic Respiratory Questionnaire (CRQ) will be assessed. For the second step we will use an anchor-based approach to estimate the MID of the STST. 6MWD and CRQ are used as anchors for which the MID has been established before.

Interventions

PROCEDUREPulmonary rehabilitation

Inpatient pulmonary rehabilitation has a duration of 3 weeks. This multimodal program consists of exercise training, breathing therapy, medical council, education and psychological support.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients with COPD (GOLD-Stage II to IV) * Ability to stand-up and walk * written informed consent

Exclusion criteria

* orthopaedic or other comorbidities that prevent patients from performing the STST, 6MWT or exercise Training * acute exacerbation * heart failure, acute coronary syndrome

Design outcomes

Primary

Measure	Time frame	Description
MID of the 1-minute-STST	21 days	Change of maximum 1-minute sit-to-stand repititions

Secondary

Measure	Time frame	Description
6-minute-walk distance	21 days	Maximal walk distance reached in 6 minutes
CRQ Score	21 days	CRQ is a health-related Quality of life questionnaire

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 23, 2026