Correlation Between Partial Oxygen Pressure and Oxygen Reserve Index

Evaluation of the Correlation Between Partial Oxygen Pressure and Oxygen Reserve Index, and Sensitivity and Specificity of Oxygen Reserve Index in Patients Undergoing Hemicolectomy

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02707796

Enrollment

240

Registered

2016-03-14

Start date

2016-05-31

Completion date

2017-11-30

Last updated

2016-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COLON CANCER

Keywords

oxygen reserve index, partial oxygen pressure, hemicolectomy

Brief summary

Oxygen reserve index (ORI) measured by multiple wave pulse co-oximeter is a new technological development in medical science. Our aim in this study is to identify the correlation between arterial oxygen pressure (PaO2) and ORI, and to identify the specificity and sensitivity of ORI as a tool to prevent hypoxia and hyperoxia in abdominal surgery patients.

Detailed description

Patients aged between 20-55 years old,American Society of Anesthesiologists physical status 1-2 who will have hemicolectomy will be included to the study. If hemodynamic instability or a sudden decrease in oxygen saturation by pulse oximetry (SpO2) occurs, arterial blood gas analysis will be taken from the patient and ORI, SpO2, PaO2, and arterial oxygen saturation (SaO2) will be recorded. The primer endpoint of the study is to identify the correlation between PaO2 and ORI, seconder end-point is to identify the specificity and sensitivity of ORI as a detector of PaO2. Pearson test for correlation, regression analysis for sensitivity and specificity will be performed. The study will include 240 patients according to power analysis

Interventions

PROCEDUREHemicolectomy

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SCREENING

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 55 Years

Healthy volunteers

Inclusion criteria

* Patients aged between 20-55 years old * American Society of Anesthesiologists physical status I-II * Patients undergoing hemicolectomy

Exclusion criteria

* Chronic obstructive and restrictive pulmonary disease * Diabetes Mellitus * Ischemic heart disease * Peripheric artery disease. * Operations longer than 200 minutes, requirement transfusion of more than 1 U erythrocyte suspension, and requirement of vasopressor or inotrope infusion will be excluded from the study

Design outcomes

Primary

Measure	Time frame
Evaluation of the correlation between partial oxygen pressure in arterial blood sample and oxygen reserve index calculated by pulse co-oximetry, and sensitivity and specificity of oxygen reserve index in patients undergoing hemicolectomy	oxygen reserve index and peripheric oxygen saturation will be recorded before and after induction of anesthesia, and every 5 minutes and arterial partial oxygen pressure in every 30 minutes during hemicolectomy.

Secondary

Measure	Time frame
Sensitivity and specificity of oxygen reserve index	During Hemicolectomy

Countries

Turkey (Türkiye)

Contacts

Primary Contactcigdem akyol beyoglu

akyolbeyoglu@gmail.com+905052278176

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026