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Risk and Risk Perception of Knee Osteoarthritis in the US

Raising Awareness of Knee Osteoarthritis (OA) and Willingness to Undertake Behavioral Changes to Reduce Risk of Knee OA: Online Recruitment

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02704286
Enrollment
380
Registered
2016-03-10
Start date
2015-04-30
Completion date
2015-05-31
Last updated
2016-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Brief summary

The investigators have created an interactive knee osteoarthritis (OA) risk calculator that estimates a user's risk of developing symptomatic knee OA as well as the user's risk for undergoing a total knee replacement (TKR) within their lifetime. To test the impact of the calculator, the investigators recruited OA-free subjects from Amazon's Mechanical Turk. Participants were randomized to either access general information about OA or use the risk calculator in addition to accessing general OA information. The investigators hypothesized that participants randomized to the risk calculator arm would have more accurate perception of their knee OA risk and would have increased willingness to change risky behavior compared to the general OA information group.

Interventions

BEHAVIORALInternet-Based Osteoarthritis Risk Calculator

The investigators have developed a personalized risk calculator for knee osteoarthritis. This risk calculator uses the Osteoarthritis Policy Model to estimate an individual's risk of developing knee osteoarthritis within their lifetime based on demographic information and risk factors. It shows this information to the user with interactive graphs and compares their risk to the risk of an average American of the same age.

BEHAVIORALGeneric osteoarthritis information

Subjects viewed generic (i.e. not personalized) information about osteoarthritis risk factors

Sponsors

Brigham and Women's Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
25 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Participants must be between the ages of 25 and 45 * Participants must live in the United States * Participants must not be diagnosed with osteoarthritis

Exclusion criteria

* All participants who did not meet the inclusion criteria

Design outcomes

Primary

MeasureTime frameDescription
Change in estimated lifetime knee OA risk1 dayThe difference between average lifetime knee osteoarthritis risk estimated by participants at baseline and average lifetime knee osteoarthritis risk estimated by participants after the intervention.
Change in estimated 10-year knee OA risk1 dayThe difference between average 10-year knee osteoarthritis risk estimated by participants at baseline and average 10-year knee osteoarthritis risk estimated by participants after the intervention.

Secondary

MeasureTime frameDescription
Reaching an Action Stage on Diet Contemplation Ladder1 dayThe percentage of subjects who originally ranked themselves below an action stage (8 or higher) on a contemplation ladder for changing diet related behaviors and who moved to an action stage after the intervention.
Reaching an Action Stage on Exercise Contemplation Ladder1 dayThe percentage of subjects who originally ranked themselves below an action stage (8 or higher) on a contemplation ladder for changing exercise related behaviors and who moved to an action stage after the intervention.
Reaching an Action Stage on Weight Control Contemplation Ladder1 dayThe percentage of subjects who originally ranked themselves below an action stage (8 or higher) on a contemplation ladder for changing weight control behaviors and who moved to an action stage after the intervention.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026