Healthy
Conditions
Brief summary
The aim of this porject is to test the Cardiospace system that integrates several medical devices to monitor the cardiovascular system: * ECG * Brachial blood pressure * Continuous finger blood pressure * Ultrasound * Laser doppler + iontophoresis Cardiospace will be used in space station to monitor the cardiovascular system of astronauts for research purpuse.
Interventions
DEVICECARDIOSPACE System
* autonomic nervous system test * tilt test * ultrasound exploration at rest (heart / vessels) * laser doppler + iontophoresis test * sub-maximal exercise test
Sponsors
National Center for Spatial Study, Toulouse
Astronaut Center of China
University Hospital, Angers
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Age : 18 to 40 years * Size : 160 à 180 * Weight : BMI between 18 and 24 * Medical history : * No history of cardiovascular disease * No chronic treatment * No syncopal events (\>2 by year) * Physical examination * Normal cardio-pulmonary ausculation * Normal (DBP \[60 - 90\] SBP \[100 - 140\] * Normal heart rate (between 50 and 80 at rest) * Complementary examination * Normal Electrocardiogram * Presence of temporal acoustic window * Capable to understand the objectives and constraints of this study * Covered by health social insurance * Have signed the informed consent
Exclusion criteria
* Pregnant woman (beta HCG by urinary test) or breastfeeding * Refusing to sign the informed consent * Don't understand the objectives of this study * Minors or majors protect by the law * Don't Benefit of social insurance * Participation at the time of study enrolment during the present trial period in another clinical trial investigating. * Having reached or surpassed the annual amount of compensation allowed by clinical trials * Receipt of any chronic and regular treatment * Presence of sign cardiovascular diseases during the questioning * Presence of sign cardiovascular diseases during the examination * Presence of sign syncopals events ATCD diseases during the questioning (\>2 by year) * Absence of temporal acoustic window with the Transcranial Doppler * Respiratory disorder, asthma * Any troubles preventing the realization of physical activity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate measure on ECG | 1 day |
Countries
France
Outcome results
None listed