Medication Review Focusing on Anticoagulation Therapy in Swiss Community Pharmacies

Durchführung Einer Beobachtungsstudie im Rahmen Einer Masterarbeit Zur Identifikation Von Pharmaceutical Care Issues Bei Patienten, Welche Mit Oralen Antikoagulantien Behandelt Werden

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02703727

Enrollment

Registered

2016-03-09

Start date

2014-11-30

Completion date

2016-12-31

Last updated

2016-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug Therapy Management

Keywords

polypharmacy, polymedication check, anticoagulation treatment

Brief summary

Oral anticoagulation therapy (OAC) entails a high potential for adverse events and strict adherence is needed.Thus, medication review and identification of safety issues and knowledge gaps about OAC is critically important. The polymedication check (PMC) is a reimbursed intermediate medication review focusing on adherence and medication management for Swiss primary care. Investigators aime to assess the impact of the PMC extended with a semi-structured interview focusing on OAC.

Interventions

BEHAVIORALExtended polymedication check

Behavioral: Medication review Patients on oral anticoagulants and polypharmacy will receive extended polymedication check to identify Pharmaceutical Care Issues, Adherence Issues, Drug related problems and Knowledge Gaps The PMC has been implemented in 2010 as a new cognitive service provided by any community pharmacist to patient with polypharmacy (n\>3 drugs) on long term conditions (\> 3 months) and is reimbursed by swiss health insurance. The semi-structured interview contains questions about knowledge on oral anticoagulation therapy. This extended PMC follows a structured predefined protocol. As an outcome, pharmacist may install a compliance support e.g. weekly filled pill organizer.

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* intake of an oral anticoagulant * more than 3 drugs over at least 3 months prior to recruitment * german language (written and spoken) * medicines use in self management

Exclusion criteria

* living in a nursing home * provision of polymedication check in the past

Design outcomes

Primary

Measure	Time frame	Description
Number of Knowledge gaps about oral anticoagulation therapy	2 Weeks	Knowledge about oral anticoagulation therapy will be assessed during the extended Polymedication check which includes 8 specific questions on oral anticoagulation knowledge. After 2 Weeks a follow-up telephone interview will be performed and the same 8 questions will be assessed.

Secondary

Measure	Time frame	Description
Medication possessio ratio (MPR)	12 Months	Medication history from pharmacy software will be used to calculate the MPR of all drugs, retrospectively starting 12 months before the extended PMC takes place.

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026