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Effect of Passive Leg Raising for Fluid Responsiveness

Effect of Passive Leg Rasing on Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02702544
Enrollment
80
Registered
2016-03-08
Start date
2016-03-31
Completion date
2016-03-31
Last updated
2016-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Body Fluid Retention, Cardiac Output, Low, Impedance

Brief summary

Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 - Haemodynamic Measurement System, Medis. GmbH Ilmenau) while lifting the leg at different angles. The measurement lasted 12 minutes.

Interventions

DEVICESCHILLER, BR-102 plus - Ambulatory Blood Pressure Monitoring System

Blood pressure monitoring every 1 min during leg elevation

Sponsors

Medical University of Warsaw
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* give voluntary consent to participate in the study * no clinical cardiovascular disease during the 6 months proceeding entry

Exclusion criteria

* not meet above criteria * episode of illness (for example: infection) * pregnancy

Design outcomes

Primary

MeasureTime frame
Changes in volumetric hemodynamic parameter- cardiac index [l/min/m2]) induced by fluid removal on leg elevation1 day

Secondary

MeasureTime frame
Changes in volumetric hemodynamic parameter- stroke volume [ml] induced by fluid removal on leg elevation1 day
Changes in volumetric hemodynamic parameter- systemic vascular resistance index [dyn·s·cm-5·m-2] induced by fluid removal on leg elevation1 day
Changes in contractility parameter- acceleration index [1/100/s-2] during leg elevation1 day
Changes in blood pressure values [mmHg] induced by fluid removal on leg elevation1 day
Changes in vascular parameter- thoracic arterial complicance [ml/mmHg/m-2] during leg elevation1 day
Changes in fluid removal parameter- thoracic fluid content [1/kOhm] during leg elevation1 day

Countries

Poland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026