Cystic Fibrosis
Conditions
Keywords
Cystic fibrosis, Backpack carrying, Respiratory function, Children
Brief summary
Cystic Fibrosis is a hereditary, chronic respiratory illness. Cystic Fibrosis leads to a progressive decline in lung function. School-aged children with cystic fibrosis experience backpack carrying everyday. Backpack carrying induce a restrictive effect responsible for lower lung function. Respiratory muscle strength is also impaired. No studies assessed aerobic capacities during children's gait while carrying a backpack. The investigators hypothesized that backpack carrying will induce an acute decline in lung function in children with cystic fibrosis compared to healthy children. Investigators also hypothesized that aerobic capacities will be impaired.
Interventions
BEHAVIORALBackpack Carrying
A 12,5% of body weight backpack will be used for each measurement. Lung function will be assessed while carrying a double strap backpack, a mono shoulder backpack and without a backpack.
Sponsors
Groupe Hospitalier du Havre
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
10 Years to 18 Years
Healthy volunteers
Yes
Inclusion criteria
* Cystic Fibrosis * School-aged children (10 to 18)
Exclusion criteria
* Backpack carrying contraindication * Acute exacerbation * Impossible gait * Other respiratory disease (asthma ...)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung Function (Forced Vital Capacity) | Immediate assessment while standing |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Respiratory Muscle Strength (MEP) | Immediate assessment while standing | Maximal expiratory pressure |
| Oxygen uptake (VO2) | During 12min treadmill gait | — |
| Lung function (Forced Expiratory Volume in 1 second) | Immediate assessment while standing | — |
| Respiratory Muscle Strength (MIP) | Immediate assessment while standing | Maximal inspiratory pressure |
| Ratio Ventilation/VCO2 (Ventilation equivalent for carbon dioxide) | During 12min treadmill gait | Number of liters of air must be ventilated to reject 1 Liter of CO2 |
| Dyspnea (Borg Scale) | During 12min treadmill gait | — |
| Ratio Ventilation/VO2 (Ventilation equivalent for oxygen) | During 12min treadmill gait | Number of liters of air must be ventilated to consume 1 Liter of O2 |
Countries
France
Outcome results
None listed