Preeclampsia
Conditions
Keywords
Preeclampsia, Antiphospholipid Antibodies
Brief summary
The purpose of this study is to determine the prevalence of positive antiphospholipid antibodies among women with preeclampsia and to determine the effect of antiphospholipid antibodies on the severity of preeclampsia and the obstetric outcomes
Detailed description
For all women included in the study, blood samples will be tested for anticardiolipin antibodies and lupus anticoagulant. The clinical details of all women will be collected by reviewing their hospital and prenatal records. The following clinical characteristics will be evaluated: maternal age, previous gestations, parity, past or family history of preeclampsia, gestational age at the onset of preeclampsia, gestational age at delivery and birth weight. The following pregnancy and delivery complications will be assessed: placental insufficiency, intrauterine growth restriction, fetal loss (stillbirth) and early neonatal death.
Interventions
OTHERTesting for antiphospholipid antibodies
Blood samples will be tested for anticardiolipin antibodies and lupus anticoagulant
Sponsors
Mohamed Sayed Abdelhafez
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
* Pregnant women with preeclampsia.
Exclusion criteria
* Women with systemic autoimmune disease. * Women with active thromboembolic disorders. * Women with history of previous thromboembolic disorders.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of positive antiphospholipid antibodies | 20 weeks to 42 weeks gestational age | Number of women having positive antiphospholipid antibodies per total number of women |
Countries
Egypt
Outcome results
None listed