Ventricular Arrhythmias After Pulmonary Vein Isolation

A Single-center Observational Study to Examine the Occurrence of Ventricular Arrhythmias After Pulmonary Vein Isolation

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02699255

Enrollment

111

Registered

2016-03-04

Start date

2014-10-31

Completion date

2017-01-27

Last updated

2019-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation, Ventricular Arrhythmias

Brief summary

The investigators study aimed to observe the occurrence of new premature ventricular complexes and other ventricular arrhythmias after pulmonary vein isolation.

Detailed description

Atrial fibrillation is the most common arrhythmia with a lifetime risk for development of over 20%. Pulmonary vein isolation is now established as therapy of choice for patients with symptomatic atrial fibrillation. It is well known that this interventional therapy inevitably modulates the intracardiac autonomic nervous system. While this ablation might alter atrial electrophysiology beneficially, the impact on ventricular electrophysiology remains unclear.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Age \> 18 years * Paroxysmal atrial fibrillation scheduled to undergo pulmonary vein isolation

Exclusion criteria

* Age \< 18 years * Persistent atrial fibrillation * Life expectancy less than 12 months * Acute myocardial infarction, coronary artery bypass graft surgery, open heart surgery, or percutaneous transluminal coronary angioplasty within less than 3 months prior to inclusion * Documentation of \>30 premature ventricular complexes per hour, salvos or ventricular tachycardias prior to atrial fibrillation ablation

Design outcomes

Primary

Measure	Time frame	Description
Ventricular arrhythmias	one year	Number of patients with premature ventricular complexes, ventricular tachycardias or ventricular fibrillation.

Secondary

Measure	Time frame	Description
Arrhythmia recurrence	one year	Number of patients with premature ventricular complexes, ventricular tachycardias or ventricular fibrillation.

Countries

Germany

Outcome results