Keratoconus
Conditions
Keywords
Keratoconus, Corneal Topography, Diagnosis, Keratomileusis, Laser In Situ
Brief summary
The main purpose of this study is to determine new diagnostic criteria for an eye disease called keratoconus.
Detailed description
Eyes of patients who distinctly present signs of keratoconus, for both eyes, at corneal tomography (an exam commonly used in such cases), and those who present such signs in only one eye were compared to eyes of unaffected patients. Several characteristics of anterior and posterior corneal astigmatism (special emphasis was given to the latter) were collectively assessed among all patients by a method referred to as vectorial analysis. Statistical tests were then performed, in an attempt to highlight differences among those three groups of patients and, eventually, define new diagnostic criteria.
Interventions
OTHERAnalysis of anterior and posterior corneal surfaces
Corneal data obtained from a Scheimpflug-based topographer were converted to astigmatic vectors in accordance to the method proposed by Thibos
Sponsors
University of Sao Paulo
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Good-quality Scheimpflug scans (approved by the device in the ''Examination Quality Specification'').
Exclusion criteria
* Previous eye surgery or trauma, and any sort of corneal scarring that might interfere with keratometric data acquisition.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Astigmatism corneal vectors (based on keratometric readings at the three millimeter optical zones for both corneal surfaces). | Through study completion, an average of 6 months. | Corneal tomography at an Scheimpflug-based tomographer |
Countries
Brazil
Outcome results
None listed