Pregnancy
Conditions
Brief summary
This study aims to investigate the impact of serum progesterone concentrations on the day of embryo transfer in egg donation cycles under hormonal replacement therapy. As secondary outcomes, the investigators will investigate if endometrial volume measured by three-dimensional (3D) ultrasound on the day of embryo transfer is related with progesterone levels and with chances of pregnancy.
Interventions
OTHERProgesterone 25-75
Impact of serum progesterone concentrations \[25-75\] on the day of embryo transfer in egg donation cycles under hormonal replacement therapy
OTHERProgesterone <25, >75
Impact of serum progesterone concentrations (\<25, \>75) on the day of embryo transfer in egg donation cycles under hormonal replacement therapy
Sponsors
Instituto Valenciano de Infertilidad, IVI VALENCIA
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
25 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Age\<50 yo * BMI \< 30Kg/m2 * Hormonal replacement cycle * Endometrial thickness \>6.5 mm during proliferative phase * Transfer of one or two blastocyst grade A-B according to ASEBIR
Exclusion criteria
* Uterine pathology * Cryptozoospermia * Severe implantation failure (\>6 GQ embryos transferred without success)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mid-luteal serum progesterone level | one year |
Secondary
| Measure | Time frame |
|---|---|
| endometrial volume | one year |
Countries
Spain
Outcome results
None listed