Malignant Neoplasm
Conditions
Keywords
Radiation therapy, Thrombosis
Brief summary
The aim of the present study is to determine the frequency and to identify main risk factors for venous thromboembolism of venous thromboembolic complications in a population of cancer patients treated with a curative intent by ionizing radiation.
Interventions
BIOLOGICALBiomarkers assays
D-Dimer assays, C-reactive protein, blood platelets assays
Sponsors
Centre Hospitalier Universitaire de Saint Etienne
CH Roanne
Institut de Cancérologie de la Loire
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patient with a solid cancer (all locations) treated with radiation therapy and / or brachytherapy as curative intent * to be 18
Exclusion criteria
* Patient with metastatic cancer, * Patients whose follow-up at 6 months is not possible * Patient receiving an anti-coagulative medication (curative doses) * Pregnant or breastfeeding women, * Person under protection of justice or unable to give consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Venous Thromboembolism event | 6 months | All venous thromboembolism, whether symptomatic or discovered incidentally, objectified (CT angiography, lung scintigraphy, venous Doppler) between J1 of radiation treatment, up to 6 months following discontinuation of radiation treatment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Dosage of D-dimer | 6 months | — |
| C-reactive protein | 6 months | — |
| Complete blood count | 6 months | — |
| Time of occurrence of VTE | 6 months | Time of occurrence of VTE |
| Symptomatic VTE | 6 months | Symptomatic VTE. |
Countries
France
Outcome results
None listed