Diaphragmatic Echography in Critically Ill patientS

Evaluation of Diaphragmatic Displacement During Spontaneous Breathing Trials in Critically Ill Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02696018

Acronym

DECIS

Enrollment

Registered

2016-03-02

Start date

2014-07-31

Completion date

2015-03-31

Last updated

2016-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Failure

Keywords

Diaphragm, Ultrasound, Critically ill patients

Brief summary

Acute respiratory failure (ARF) is characterised by a discrepancy between load imposed on respiratory muscles and their capacity. Recently, diaphragmatic ultrasonography has been introduced in the clinical practice to evaluate diaphragmatic function. In particular, the investigators will focus on Diaphragmatic Displacement measured by M-mode ultrasonography. The aim of this study was to compare the diaphragmatic displacement with traditional weaning parameters in potentially ready to be extubated patients undergoing a spontaneous breathing trial (SBT).

Interventions

DEVICEUltrasonography

Ultrasonographic assessment of the diaphragm function

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* mechanically ventilated since more than 24 hours * clinical improvement of the underlying acute cause of the respiratory failure * adequate cough reflex * absence of excessive and/or purulent tracheobronchial secretion * stable cardiovascular status * stable metabolic status * adequate pulmonary function * adequate mentation

Exclusion criteria

* age \<18 years * pregnancy * presence of thoracostomy, pneumothorax or pneumomediastinum * presence of flail chest or rib fractures * neuromuscular disease * use of muscle-paralyzing agents within 48 hours before the study * history or new detection of paralysis or paradoxical movement of a single hemi-diaphragm on diaphragm ultrasonography

Design outcomes

Primary

Measure	Time frame	Description
Weaning success	within the first 48 hours after the spontaneous breathing trial	A successful weaning attempt was registered when patients were extubated and breathed spontaneously for more than 48 hours. The reinstitution of mechanical ventilation at the end of spontaneous breathing trial, reintubation within 48 hours or non-invasive ventilation (NIV) support after extubation defined a failed weaning attempt.

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 12, 2026