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The Effect of Obesity on Endometrium in PCOS

Effect of Body Weight on Endometrial Ultrasonographic Characteristics in Polycystic Ovary Syndrome Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02694419
Acronym
OB-PCO
Enrollment
100
Registered
2016-02-29
Start date
2016-02-29
Completion date
2017-04-30
Last updated
2017-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Body Weight, Polycystic Ovary Syndrome

Keywords

endometrium

Brief summary

The effect of Polycystic Ovary Syndrome (PCOS) with or without obesity has received a few attentions. There is a lack of evidence to whether the BMI affects the endometrial blood flow, which is necessary for implantation.

Interventions

Endometrial volume, endometrial and subendometrial vascularity indices are measured by 3D power Doppler

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* Women with PCOS are diagnosed according to Rotterdam criteria, (Rotterdam and ASRM-Sponsored, 2004)by the presence of two out of the following three: oligomenorrhea (absence of menses for 35-182 days) or amenorrhea (absence of menses for \>182 days), signs or symptoms of hyperandrogenism (acne, hirsutism), US showing polycystic ovaries. * Fertile women had regular menstruation, with at least one previous spontaneous pregnancy.

Exclusion criteria

* Women known to have hepatic or renal dysfunction, Diabetes mellitus, hypertension, or cardiovascular disease. * If they have used induction of ovulation drugs for the last three months. * If they have used hormonal contraception in the last three months.

Design outcomes

Primary

MeasureTime frame
the mean difference in Doppler indices (VI-FI-VFI)24 hours

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026