Gastric Cancer
Conditions
Keywords
reflux, residue, Gastric stasis, Emptying time
Brief summary
The Advantages and Disadvantages Between Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction After Laparoscopy-assisted Distal Gastrectomy for Gastric.
Detailed description
To search which is the better reconstructions by comparing and analyzing the advantages and disadvantages between Uncut Roux-en-Y and Billroth II reconstructions after laparoscopy-assisted distal gastrectomy for gastric cancer. Method: It's a prospective study including all patients underwent laparoscopy-assisted distal gastrectomy (LADG) in the First Hospital of Jilin University, from February 2016 to February 2017. All surgical procedures will be performed by the single surgery team, which is leaded by professor Wang Quan. The reconstruction method will be selected randomly from Uncut Roux-en-Y and Billroth II anastomosis by drawing lots preoperatively without distinct indications. Clinical data, operation data and perioperative complications and related physiological indexes of differences.
Interventions
PROCEDUREUncut Roux-en-Y Reconstruction
All surgical procedures will be performed by the single surgery team ,which is leaded by professor Wang Quan. Uncut Roux-en-Y construction will be used in this group.
PROCEDUREBillroth II Reconstruction
All surgical procedures will be performed by the single surgery team ,which is leaded by professor Wang Quan. Uncut Roux-en-Y construction will be used in this group.
Sponsors
Jilin University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
No minimum to 85 Years
Healthy volunteers
No
Inclusion criteria
* Clinical diagnosis of distal gastric cancer * underwent laparoscopy-assisted distal gastrectomy
Exclusion criteria
* have simultaneously other cancer * have severe systemic inflammatory disease ,serious illness such as diabetes, chronic lung diseases * have upper gastrointestinal surgery * can't bear the gastric tube * the period is too late or the tumor is too large to carry on a laparoscopy assisted radical distal gastrectomy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The time of reconstruction during operations of Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction | within 2 hours after surgery | The time of reconstruction operation will be recorded in the operating note by nurses in minutes. |
| change of potential of hydrogen ( pH) in remnant stomach | 1-6 days after surgery | In the morning of 1-6 days after operation , monitor the number of gastric juice's potential of hydrogen ( pH) value through gastric tube and write down the data. So if the data is greater than 7,the complication of bile reflux happened |
| the amount of blood loss during operations of Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction | within 2 hours after surgery | During the operation the amount of blood loss will be recorded in the operating note by nurses in milliliters. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the number of patients with the complication of Residual food | 6 month after surgery | During the upper gastrointestinal radiography，if there is residual food,the meglumine diatrizoate will be separate and then write down the number. |
| the number of patients with the complication of Reflux esophagitis | 6 month after surgery | During the upper gastrointestinal radiography,if there is meglumine diatrizoate refluxing to esophagus,it will be observed and written down in number. |
Other
| Measure | Time frame | Description |
|---|---|---|
| the number of patients with the complication of gastroesophageal reflux disease(GERD) | 6 month after surgery | all patients of this clinical trial will be investigated by Gastroesophageal reflux disease questionnaire(GerdQ),and all patients whose score is beyond 8 will be collected. |
Countries
China
Contacts
Primary ContactDong Yang, postgraduate
Outcome results
None listed