Brain Injuries
Conditions
Brief summary
The main objective of this study is to examine the effect of Goal Management Training for patients with executive difficulties after acquired brain injury in a randomized controlled trial. The effect on cognitive functioning will be examined, as will the relationship between treatment effects and lesion location and size. The effect of Goal Management training on regulating emotions, quality of life and coping will be examined. The generalizability of treatment effects across etiologies will be explored by comparing effects in three patient groups; traumatic brain injury, cerebrovascular accidents and resected brain tumors. Structural Magnetic Resonance Imaging (MRI) scans and measures of white matter connectivity will be used to establish detailed lesion descriptions. Functional MRI data will provide information on the neural underpinnings of treatment related change. A secondary objective is to expand the Goal Management Training protocol with increased focus on emotional regulation and adherence to homework assignment.
Interventions
Goal Management training, 8 sessions of 2 hours
Brain Health Workshop training, 8 sessions of 2 hours
Sponsors
University of Oslo
University of Glasgow
Oslo University Hospital
Sunnaas Rehabilitation Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 67 Years
Healthy volunteers
No
Inclusion criteria
* Traumatic Brain Injury, stroke and resected brain tumor patients with no concomitant diseases * Minimum 6 months post-injury/surgery * Reporting executive problems by structured interview or baseline assessment (cognitive performance measures)
Exclusion criteria
* Major psychiatric disorder or reported ongoing alcohol or substance abuse * Premorbid neurological disease or insult and/or comorbid neurological disease * Aphasia or other specified language problems causing potential communication problems * Impaired basic cognitive, linguistic, mnemonic, motor, or perceptual function that can interfere with the ability to engage with the training
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Executive functioning in daily life measured by self report questionnaire | one year | Behavior Rating Inventory Executive Functions Adult version |
| Executive functioning measured by neuropsychological assessment | one year | Conners Continous Performance Test |
Outcome results
None listed