Hyaluronic Matrix Efficacy for Maxillary Sinus Augmentation

Evaluation of Hyaluronic Matrix, Used With Xenograft, Efficacy in Sinus Augmentation by Histomorphometry and Micro Computed Tomography

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02692261

Enrollment

Registered

2016-02-26

Start date

2014-09-30

Completion date

2015-12-31

Last updated

2016-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sinus; Dental

Brief summary

Sinus augmentation is a predictable method when alveolar bone height is not sufficient for dental implant placement in posterior maxillary alveolar region..The aim of this prospective, randomized, controlled clinical study is comparison of hyaluronic acid originated matrix and equine derived xenograft with only xenograft use in sinus augmentation by micro computed tomography and histomorphometry.

Interventions

PROCEDUREMaxillary Sinus Augmentation

Each 0.5 cc Collagenated Heterolog Bone Graft, mixed with two bundles of Hyalossᵀᴹ matrix and a few drops of sterile saline solution

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

33 Years to 69 Years

Healthy volunteers

Yes

Inclusion criteria

* Systemically healthy patients * Requiring bilateral maxillary sinus augmentation (residual crest height ≤ 4 mm)

Exclusion criteria

* Advanced systemic diseases * Chronic medication use * Maxillary sinus disease * Current pregnancy * Lactation * Smoking habit

Design outcomes

Primary

Measure	Time frame	Description
Percentage of newly formed bone calculated from bone biopsises by Micro-CT and Histomorphometry	4 months after surgery	Biological parameter obtained by analyzing bone biopsises

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026