Postoperative Pain
Conditions
Brief summary
Patients undergoing abdominal procedures often require multimodal postoperative pain controls. Truncal blocks such as quadratus lumborum (QL) block may be used adjunctively as a part of it. The investigators hypothesized that the ultrasound-guided QL block with transmuscular approach can provide adequate pain relief for colostomy closure as part of a multimodal pain control.
Interventions
DRUGlevo-bupivacaine
DRUGnormal saline
Sponsors
Sun Yat-sen University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* A physical status between ASA I and III * 20 - 75 years of age * Patient has signed an informed consent * Without contraindication of QL block
Exclusion criteria
* American Society of Anesthesiologists (ASA) Physical Status ≥ 4 * Any contraindication to nerve blocks (including coagulopathy, abnormal anatomy, infection at the planned QL injection site, and amide-type local anesthetic allergy) pregnancy or breast-feeding * Severe obesity (body mass index≥ 35 kg/m2) * Patients with a history of significant neurological, psychiatric, neuromuscular, cardiovascular, pulmonary, renal or hepatic disease * Allergy to NSAIDs * Infection at the QL injection site * Patients with major psychosis or drug and alcohol abuse * Patient unable to comprehend or use the verbal rating pain scoring system or patient-controlled analgesia pump
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cumulative morphine consumption | 1 hour |
Outcome results
None listed