Different Regulation of Immune Cells in Patients With Preeclampsia

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02691364

Enrollment

Registered

2016-02-25

Start date

2016-04-30

Completion date

2017-06-30

Last updated

2016-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preeclampsia, Pregnancy

Brief summary

Adaptation of the maternal immune system to accommodate the semi-allogeneic fetus is necessary for pregnancy success. Dysregulation of this immune adaptation is implicated in reproductive disorders as infertility, recurrent miscarriage, fetal growth restriction, and preeclampsia. The mechanisms being responsible for fetal tolerance are not known. Several T cell subsets have been implicated in fetal tolerance. The effects of preeclampsia on memory cells are not known. The main objective of this study is to analyze the effect of preeclampsia on levels of immune cells.

Interventions

PROCEDUREBlood withdrawal

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Inclusion criteria

* healthy * written informed consent * 18-40 years

Exclusion criteria

* smoking * immune related disorders (other than preeclampsia) * fever / illness within the last month * infertility * body mass index \<18 or \>30

Design outcomes

Primary

Measure	Time frame
Cell levels	1 year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026