Effect of Resistant Wheat Starch on Subjective Appetite and Food Intake in Healthy Adults

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02689791

Enrollment

Registered

2016-02-24

Start date

2012-01-31

Completion date

2014-08-31

Last updated

2016-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Feeding Behavior

Keywords

Appetite, Food Intake, Satiety Hormones

Brief summary

A randomized, single-blind, cross-over study was conducted to determine the effect of replacing standard wheat flour (SWF) with resistant wheat starch (RWS) on markers of appetite and food intake in healthy adults.

Interventions

DIETARY_SUPPLEMENTResistant Starch Type 4

single dose 26g fiber given at the breakfast meal

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* BMI 18.5-29.9 kg/m2 * Regular breakfast consumers (\>5 days/week)

Exclusion criteria

* not weight stable (?3 kg weight change in previous 3 months) * use/used tobacco products * presence of acute or chronic illness * restrained eater (\>13 on the restraint section of the three-factor eating questionnaire)

Design outcomes

Primary

Measure	Time frame	Description
Caloric intake	Single Day	calories consumed at post-treatment lunch meal and total calories consumed on the treatment day

Secondary

Measure	Time frame	Description
Visual analogue scale measures of subjective appetite	Single Day	0-100mm scale to assess hunger, fullness, thirst, desire to eat and prospective consumption
Serum concentrations of biomarkers of appetite	150 minutes	CCK, ghrelin, PYY3-36 and GLP-1
Plasma concentrations of biomarkers of glycemic response	150 minutes	Glucose, Insulin, GLP-1

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026