Evaluating the Addition of Regional Analgesia to Reduce Postoperative Delirium in Patients Having Hip Fracture Surgery.

The Use of Post-operative Regional Analgesia Rather Than Systemic Analgesia to Decrease the Incidence of Post-operative Delirium After Acute Hip Fracture Surgery? A Prospective Randomized-controlled Double-blinded Pilot Study.

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02689388

Acronym

RASAPOD

Enrollment

Registered

2016-02-24

Start date

2016-08-28

Completion date

2018-12-31

Last updated

2021-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delirium, Hip Fracture

Keywords

analgesia, regional analgesia, femoral nerve block, older persons, frail

Brief summary

Post operative delirium is common after hip fracture surgery and is associated with increased length of hospital stay, delayed recovery and increased mortality. Postoperative delirium can also decrease a patient's quality of life and increase treatment costs. Anesthesia and pain relief (analgesia) treatments may also influence the incidence of delirium, but more research is needed into which techniques are effective in improving patient outcomes, care and decreasing costs. This pilot study compares the addition of regional analgesia as part of general anesthesia to determine the incidence of delirium following hip surgery. This is a collaborative study involving anesthesia, orthopedic surgery and geriatrics in the improvement of patient care.

Interventions

PROCEDUREFemoral Nerve Block

Use of femoral nerve block as part of general anesthesia

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

(must meet all 3): * Greater than or equal to 65 years * Have a hip fracture requiring surgery * Written informed consent for participation of study prior to surgery.

Exclusion criteria

* Contraindication to peripheral nerve block or local anaesthetics * Unable to do delirium or cognitive testing due to language, vision or hearing impairment * Unable to communicate with research staff due to language barriers * History of chronic opioid use (longer than 1 month) * Contraindication to general anesthesia

Design outcomes

Primary

Measure	Time frame	Description
The incidence of post-operative delirium after hip fracture surgery	immeidately to 5 days post operatively	Identify the our local incidence of post operative delirium diagnosed with 3D-CAM (3 Minute Diagnostic Assessment for Confusion Assessment Method)

Secondary

Measure	Time frame	Description
Decreased recovery time after surgery	immediately - immediately - 90 days	reduction in length of stay and recovery time
Decrease post-operative opioid consumption	immediately - immediately - 90 days	reduction in the requirement for systemic/opiod analgesia

Countries

New Zealand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026