Central Venous Catheterization Techniques in Neonates

Randomized Controlled Trial on Central Venous Catheterization Techniques in Neonates: Seldinger Versus Modified Seldinger

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02688595

Enrollment

120

Registered

2016-02-23

Start date

2016-03-31

Completion date

2017-09-30

Last updated

2018-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Catheterization, Central Venous

Keywords

Infant, Newborn, Ultrasonography

Brief summary

The purpose of this study is to compare the differences in central venous catheter insertion time, success rate, and complication between the Seldinger and modified Seldinger technique for ultrasound-guided central venous catheterization in neonates.

Interventions

DEVICEUltrasound

Ultrasound-guided central venous catheterization in internal jugular vein

OTHERGeneral anesthesia

Scheduled operation under general anesthesia

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

1 Days to 1 Months

Healthy volunteers

Inclusion criteria

* surgery under general anesthesia * require central venous catheterization

Exclusion criteria

* central vein anomaly * hematoma in central vein * catheterization site infection

Design outcomes

Primary

Measure	Time frame
First successful central venous catheterization rate	Interval between skin penetration of the needle or angiocatheter and installation of the indwelling catheter, an expected average of 3 minutes

Secondary

Measure	Time frame
Time to guide wire insertion	Interval between skin penetration and removal of the needle or angiocatheter after guide wire insertion, an expected average of 90 seconds
Total time to central venous catheterization	Interval between skin penetration of the needle or angiocatheter and installation of the indwelling catheter, an expected average of 3 minutes
Number of central vein puncture trial	up to 5 times, an expected average observation time of 30 seconds
Time to first puncture of central vein	Interval between skin penetration of the needle or angiocatheter and flashback of blood, an expected average of 30 seconds
First successful central vein puncture rate	Interval between skin penetration of the needle or angiocatheter and flashback of blood, an expected average of 30 seconds
First successful guide wire insertion rate	Interval between skin penetration and removal of the needle or angiocatheter after guide wire insertion, an expected average of 90 seconds
Number of guide wire insertion trial	up to 5 times, an expected average observation time of 90 seconds

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 5, 2026